Figure 1
Distribution of Age at onset of Essential Tremor.
Table 1
Overview of medication use in 1074 ET patients.
| Confirmed cases of ET with treatment data | 1074 |
| No treatment | 291 (27.1%) |
| One medication | 500 (46.5%) |
| Two medications | 196 (18.2%) |
| Three medications | 66 (6.1%) |
| Four or more medications | 21 (2.0 %) |
| Total number of prescriptions | 1172 |
| Primidone | 546 (46.6%) |
| Propranolol | 419 (35.8%) |
| Topiramate | 122 (10.4%) |
| Gabapentin | 35 (3.0%) |
| Benzodiazepines (clonazepam + diazepam) | 24 (2.0%) |
| Metoprolol | 20 (1.7%) |
| Atenolol | 3 (0.2%) |
| Nadolol | 3 (0.2%) |
| Total number of Rx w/medication response | 1030 |
| Side effects leading to discontinuation | 138 |
| No response | 180 |
Figure 2
Tremor response based on individual treatment.
Table 2
Non-pharmacological treatments provided to ET patients.
| Number of patients receiving botulinum toxin (n = 1074) | 52 (4.8%) |
| 2001–2006 | 10 (19.2%) |
| 2007–2012 | 14 (26.9%) |
| 2013–2018 | 28 (53.8%) |
| Mean age at first injection | 67.8 ± 11.4 |
| Mean number of treatment visits | 5.2 |
| Median number of treatments | 4 |
| Medications + Botulinum toxin | 47 (90.4%) |
| Unilateral limb injections | 27 (51.9%) |
| Bilateral limbs injections | 25 (48.1%) |
| Muscle Distribution Pattern (n = 52) | |
| Forearm flexors | 49 (94.2%) |
| Supinators | 23 (44.2%) |
| Forearm extensors | 19 (36.5%) |
| Pronator teres | 10 (19.2%) |
| Number of patients receiving DBS (n = 1074) | 41 (3.8%) |
| Unilateral VIM (n = 41) | 4 (9.8%) |
| Unilateral VIM (n = 41) | 37 (90.2%) |