Table 1
Comparison of different methods for six components of the TETRAS.
| TETRAS components | Mean (S.D.) Method 1 | Mean (S.D.) Method 2 | Paired measures t test (p value) | Paired Samples Correlation | Size Effect d |
|---|---|---|---|---|---|
| Postural tremor Unilateral vs. bilateral | Unilat 1.655 (0.594) | Bilat 1.519 (0.724) | t (21) = 2.022 p = 0.056 | r = 0.903 p < 0.001 | 0.43 |
| Wing-beating Unilateral vs. bilateral | Unilat 1.996 (0.862) | Bilat 1.766 (0.912) | t (23) = 3.521 p = 0.002 | r = 0.936 p < 0.001 | 0.72 |
| Tremor Postural Wing Unilateral vs. bilateral | Unilat 1.833 (0.757) | Bilat 1.648 (0.828) | t (45) = 3.948 p < 0.001 | r = 0.923 p < 0.001 | 0.58 |
| Heel to shin Supine vs. sitting | Supine 0.310 (0.267) | Sitting 0.461 (0.290) | t (23) = 2.651 p = 0.014 | r = 0.502 p = 0.013 | 0.54 |
| Handwriting (photo vs. video) | Photo 1.938 (1.113) | Live video 1.827 (1.169) | t (11) = 1.452 p = 0.174 | r = 0.974 p < 0.001 | 0.42 |
| Spirals (photo vs. video) | Photo 2.482 (1.008) | Live Video 2.402 (0.955) | t (23) = 1.784 p = 0.088 | r = 0.976 p < 0.001 | 0.36 |
| Spirals & handwriting (photo vs. video) | Photo 2.301 (1.065) | Live Video 2.210 (1.051) | t (35) = 2.333 p = 0.026 | r = 0.976 p < 0.001 | 0.39 |
| Cursive vs. Script | Cursive 1.768 (0.976) | Script 1.536 (0.824) | t (23) = 1.819 p = 0.082 | r = 0.772 p < 0.001 | 0.37 |
Figure 1
Mean scores (N = 15 raters in A-D and N = 16 raters in E) comparison of individual tremor subjects. Blue shows lower score in second measure, red denotes higher score in second measure. A. Postural tremor done individually vs. done concurrently, B. Wing-Beating tremor done individually vs. done concurrently, C. Heal to shin done while supine vs. while done sitting, D. Combined handwriting and spiral scores when rated only by a photograph vs. when video was also viewed of the subject performing the task, E. Comparison of cursive writing vs. script writing.
Table 2
Intraclass Correlation Coefficient (ICC) of different methods for six components of the TETRAS.
| TETRAS components | ICC | Lower Bound | Upper Bound |
|---|---|---|---|
| Postural tremor Unilateral | 0.983 | 0.971 | 0.992 |
| Postural tremor Bilateral | 0.982 | 0.970 | 0.991 |
| Wing-beating Unilateral | 0.992 | 0.986 | 0.996 |
| Wing-beating Bilateral | 0.989 | 0.980 | 0.995 |
| Heel to shin Supine | 0.801 | 0.666 | 0.899 |
| Heel to shin Sitting | 0.797 | 0.661 | 0.897 |
| Cursive | 0.963 | 0.935 | 0.982 |
| Script | 0.956 | 0.921 | 0.979 |
| Spiral | 0.966 | 0.908 | 0.994 |
| Handwriting | 0.963 | 0.848 | 0.999 |
[i] 95% Confidence Interval.