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Sensorimotor Integration and GABA-ergic Activity in Embouchure Dystonia: An Assessment with Magnetoencephalography Cover

Sensorimotor Integration and GABA-ergic Activity in Embouchure Dystonia: An Assessment with Magnetoencephalography

Open Access
|Sep 2019

Abstract

Background: Embouchure dystonia (ED) is a task-specific dystonia affecting musicians thought to be related to alteration in sensorimotor processing and loss of cortical inhibition.

Case Report: Magnetoencephalography-coherence source imaging (MEG-CSI) was used to map connectivity between brain regions by imaging neuronal oscillations that are coherent across the brain in patient with ED at rest and while using the index finger to evoke dystonia normally triggered by playing the flute.

Discussion: During rest, there was increased coherence in the bilateral frontal and parietal regions that became more focal during dystonia. Diffuse hyperexcitability and increased coherence persisted in bilateral parietal regions as well as the bilateral frontal regions.

DOI: https://doi.org/10.5334/tohm.487 | Journal eISSN: 2160-8288
Language: English
Submitted on: Jul 29, 2019
Accepted on: Aug 29, 2019
Published on: Sep 24, 2019
Published by: Columbia University Libraries/Information Services
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2019 Bisena Bulica, Christos Sidiropoulos, Abhimanyu Mahajan, Andrew Zillgitt, Patricia Kaminski, Susan M. Bowyer, published by Columbia University Libraries/Information Services
This work is licensed under the Creative Commons License.