Table 1
Cases Reported in the Literature of Drug-induced Hemichorea
| Sex/Age (years) | History | Hemichorea | Brain MRI | Drug | Mechanism of Action | References |
|---|---|---|---|---|---|---|
| M/41 | None | Right | Normal | Gabapentin | Binds to many transmembrane sites within the central nervous system embracing the α-2-δ subunit of the voltage-gated calcium | Lai et al.8 |
| F/76 | Alzheimer disease | Right upper limbDystonia left lower limb | NA | Memantine | Non-competitive antagonist of NMDA receptor, dopaminergic action at high doses | Borges et al.4 |
| F/92 | Hypertension | Right | Normal | Zolpidem/zopiclone | Agonist GABA A | Watari and Tokuda5 |
| F/17 | Irregular menstrual cycle | Right | NA | Oral contraceptive pills (ethinyl estradiol and cyproterone acetate) | Competitive inhibition of the binding of testosterone and dihydrotestosterone to androgen receptorsDopaminergic action at high doses | Sharmila and Babu6 |
| M/53 | HypertensionRight frontal hemorrhage | Left | Right frontal hemorrhage | Valproate | Inhibitory GABA, excitatory NMDA receptor and sodium channel pathways | Srinivasan and Lok9 |
| F/65 | Depression | Left | Normal | Sertraline | Selective serotonin reuptake inhibitor | Present case, 2017 |
