Table 1
Published Cases of Pallidal DBS in Meige Syndrome and Isolated Blepharospasm
| Number of Patients | Indication for DBS | Follow-up Duration (months) | Improvement in Blepharospasm (%)1 | Reference no. |
|---|---|---|---|---|
| 1 | Meige | 6 | Improved but not quantified | 7 |
| 11 | Meige | 12 | 63 | 8 |
| 5 | Meige | 10–124 | 88 | 9 |
| 6 | Meige | 6 | 79 | 5 |
| 6 | Meige | 12 | Improved in all patients but not quantified | 10 |
| 12 | Meige | 12–78 | 55 | 6 |
| 1 | Isolated blepharospasm | 1 | 63 | 12 |
| 1 | Isolated blepharospasm | 15 | 88 | 13 |
Figure 1
Subject Photographs and MRI Imaging. (A) Subject’s blepharospasm pre- and post implantation of DBS. Pre-DBS, the subject used tape to hold his eyelids open. (B) T2-weighted MRI showing trajectory planning and T1-weighted images showing electrode placement in bilateral GP. DBS, Deep Brain Stimulation; GP, Globus Pallidus; MRI, Magnetic Resonance Imaging.
Table 2
Dystonia Severity at Baseline and Follow-up
| Baseline | 1 Month Post Operation (improvement from baseline) | 1 Year Post Operation (improvement from baseline) | |
|---|---|---|---|
| BFMDRS total movement score | 15 | 6 (60%) | 1.5 (90%) |
| BFMDRS blepharospasm score | 8 | 4 (50%) | 0 (100%) |
| BFMDRS neck score | 4 | 0.5 (88%) | 0.5 (88%) |
| BFMDRS disability score | 10 | 2 (80%) | 2 (80%) |
| JRS score | 8 | 4 (50%) | 0 (100%) |