Table 1
Comparative Results between HDL2, HD, and Control Groups
| HDL2 | HD | Control | |
|---|---|---|---|
| Number of participants | 12 | 13 | 21 |
| Age (years) | |||
| Mean age (SD) | 49.2 (±9.5) | 46.8 (±13.2) | 49.5 (±14.9) |
| Median age | 49 | 47 | 52 |
| Range | 32–66 | 32–68 | 21–79 |
| Disease duration (years) | |||
| Mean duration of disease (SD) | 5.9 (±4.3) | 8.2 (±4.7) | – |
| Median duration of disease | 6 | 6 | |
| Range | 1–18 | 4–18 | |
| Triplet repeat length | |||
| Mean abnormal repeat length (SD) | 46.3 (±3.3) | 44.3 (±4.5) | – |
| Median abnormal repeat length | 45 | 46 | – |
| Range | 43–53 | 40–49 | |
| Hematology results | |||
| Smear results | |||
| Wet smear (defined as >3.7% erythrocytes being acanthocytes) | |||
| Positive (number of patients) | 0 | 0 | 0 |
| Dry smear (defined as >1.2% erythrocytes being acanthocytes) | |||
| Positive (number of patients) | 0 | 0 | 0 |
| Median % of acanthocytes (IQR) | 0.21 (0.06–0.44) | 0.06 (0.00–0.11) | 0.06 (0.02–0.14) |
| Erythrocyte analysis (SD) | |||
| Hemoglobin (g/dL) | 14.62 (±1.40) | 14.28 (±2.05) | 15.56 (±3.99) |
| Red cell count (1012/L) | 5.01 (±0.63) | 4.91 (±0.47) | 5.08 (±0.56) |
| MCV (fL) | 88.1 (±4.2) | 87.1 (±5.6) | 87.4 (±4.9) |
| MCH (pg) | 29.5 (±2.0) | 29.1 (±2.6) | 29.1 (±2.0) |
| MCHC (g/dL) | 33.3 (±1.5) | 33.3 (±1.5) | 33.3 (±1.2) |
| RDW (%) | 13.3 (±0.9) | 13.7 (±1.4) | 13.6 (±0.8) |