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Digitizing Tablet and Fahn–Tolosa–Marín Ratings of Archimedes Spirals have Comparable Minimum Detectable Change in Essential Tremor Cover

Digitizing Tablet and Fahn–Tolosa–Marín Ratings of Archimedes Spirals have Comparable Minimum Detectable Change in Essential Tremor

Open Access
|Jul 2017

Figures & Tables

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Figure 1

Distributions of Mean FTM Spiral Ratings and Log Tremor Amplitudes. Notched box and whisker plots of mean FTM spiral ratings and tablet measures are shown for the two baseline assessments. The baseline medians did not differ significantly for either measure of tremor severity. The FTM data exhibit a floor effect at 0. FTM, Fahn–Tolosa–Marín.

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Figure 2

Linear Regression Equations for Log10 Tremor Amplitude vs. FTM. Regression lines (blue) and 95% confidence intervals (red broken lines) are shown for log mean tremor amplitude vs. mean FTM spiral rating for baseline 1 and 2 assessments. FTM, Fahn–Tolosa–Marín.

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Table 1

Minimum Detectable Change Results for FTM and Tablet Measures of Tremor Amplitude

FTM Mean (cm)SDd FTM Baseline 1–2Tablet Geometric Mean (cm)SDd Tablet Baseline 1–2MDC%
FTMTablet
Baseline 10.880.410.200.16490%151%3
Baseline 20.940.1967%2

Abbreviations: FTM, Fahn–Tolosa–Marín; MDC, Minimum Detectable Change (SDd·1.96); SDd: Standard Deviation of the Differences.

1 MDC%: percentage of baseline 1 mean FTM.

2 MDC%: percentage of baseline 1 mean FTM, computed with the Weber–Fechner equations in Figure 2.

3 MDC%: percentage of baseline 1 geometric mean.

4 SDd of log-transformed data.

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DOI: https://doi.org/10.5334/tohm.344 | Journal eISSN: 2160-8288
Language: English
Submitted on: May 20, 2017
Accepted on: Jun 20, 2017
Published on: Jul 7, 2017
Published by: Columbia University Libraries/Information Services
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2017 Rodger J Elble, Aaron Ellenbogen, published by Columbia University Libraries/Information Services
This work is licensed under the Creative Commons License.