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Alien Limb Syndrome Responsive to Amantadine in a Patient with Corticobasal Syndrome Cover

Alien Limb Syndrome Responsive to Amantadine in a Patient with Corticobasal Syndrome

Open Access
|Jun 2015

Figures & Tables

Video 1

Segment 1. Before Amantadine Treatment. Forced, painful, retrograde elevation of the right arm. The patient can be seen constantly holding her right arm with her left hand to prevent the alien movement. The video also details the difficulty that the patient experienced performing simple tasks with her right hand, because the right hand was acting on its own. Segment 2. After Amantadine Treatment. Although significant right arm paresis is evident, forced arm elevation is minimally evident and she can perform simple tasks with her right arm much better. Occasionally one can see that mild to moderate alien hand symptoms persisted. Significant apraxia is also quite evident, i.e. the patient could not clap her hands and tried but could not show how to comb her hair with her hands.

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Figure 1

Brain Magnetic Resonance Imaging. (a) The T1 sequence demonstrates generalized atrophy (including significant atrophy of the temporal lobes), more pronounced on the frontal lobes and brainstem, without significant asymmetry or selective midbrain involvement. (b) The T2 sequence also reveals mild, mainly periventricular white matter disease (leukoaraiosis) and lacunar strokes.

DOI: https://doi.org/10.5334/tohm.253 | Journal eISSN: 2160-8288
Language: English
Submitted on: Mar 23, 2015
Accepted on: May 19, 2015
Published on: Jun 23, 2015
Published by: Columbia University Libraries/Information Services
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2015 Francisco de Assis Aquino Gondim, José Wagner Leonel Tavares Júnior, Arlindo A. Morais, Paulo Marcelo Gondim Sales, Horta Goes Wagner, published by Columbia University Libraries/Information Services
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.