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The Progression of Posterior Cortical Atrophy to Corticobasal Syndrome: Lumping or Splitting Neurodegenerative Diseases? Cover

The Progression of Posterior Cortical Atrophy to Corticobasal Syndrome: Lumping or Splitting Neurodegenerative Diseases?

Open Access
|Jun 2014

Abstract

Background: Posterior cortical atrophy is a clinical syndrome that is characterized by the progressive loss of visuospatial integration and is associated with neurodegenerative conditions.

Case Report: We describe a 60-year-old female with simultanagnosia, oculomotor apraxia, and optic ataxia for which she received an initial clinical diagnosis of posterior cortical atrophy. Three years later, she developed Balint’s syndrome, Gerstmann’s syndrome, left alien hand syndrome, smooth asymmetric (left) rigidity, cortical sensory loss, and spontaneous myoclonic jerks of the left arm, which suggested a final diagnosis of corticobasal syndrome.

Discussion: This case report indicates that corticobasal syndrome may present with visuospatial deficits.

DOI: https://doi.org/10.5334/tohm.207 | Journal eISSN: 2160-8288
Language: English
Submitted on: Apr 16, 2014
Accepted on: May 23, 2014
Published on: Jun 24, 2014
Published by: Columbia University Libraries/Information Services
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2014 Maurizio Giorelli, Nunzia Alessandra Losignore, Junia Bagnoli, Pasquale Difazio, Giovanni Bosco Zimatore, published by Columbia University Libraries/Information Services
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.