TABLE 1
Striatal Binding of Cases 1, 2, and 3.
| Striatal Binding | Case 1 | Case 2 | Case 3 | Healthy Controls (mean±SD, n = 7) |
|---|---|---|---|---|
| Right caudate | 1.01 | 1.51 | 1.86 | 1.94±0.56 |
| Left caudate | 1.10 | 0.84 | 1.85 | 1.98±0.43 |
| Right putamen | 0.56 | 0.81 | 1.83 | 1.75±0.38 |
| Left putamen | 0.60 | 0.40 | 1.70 | 1.83±0.41 |
[ii] This parameter was calculated as a specific binding ratio relative to the occipital lobe as a reference tissue. The striatal specific binding ratio is calculated as: (S-O)/O. Where, S is activity in the striatum (caudate or putamen) and O is the activity in the occipital lobe. Any positive number indicates higher binding in the striatum than in the reference region. The reference normal striatal binding values were obtained in seven healthy controls.
Figure 1
[123I]-FP-CIT SPECT scan images.
Case 1, Case 2, and Case 3, respectively. The images were interpreted by a nuclear medicine physician (Z.S.) using established criteria and were quantitatively analyzed using the BRASS software (Hermes Medical Solutions, Stockholm Sweden). The quantification program is objective since it is entirely operator independent.