Table 1.
Mount Sinai Case Series
| Patient # | Age/Sex | Onset Age | Duration (yrs) | Limb | Precipitant Movement Task | Phenomenology | Present at Rest | Other Limbs Affected | FH | Medications | Response |
| 1 | 31/M | 26 | 5 | R | Walking down steps | Plantarflexes foot and flexes hip when walking down steps. Absent while walking up steps or backward. | No | None | PD | Sinemet | None |
| 2 | 24/F | 20 | 4 | L | Marathon running | Inversion and plantarflexion of the foot while walking that becomes more prominent with running. Does not occur when walking backward. | No | None | None | Sinemet | None |
| 3 | 33/F | 31 | 2 | R | Marathon running | Sustained inversion while walking, which normalizes while walking backward. Improves with side stepping in either direction as well as walking forward while imagining walking backward. | No | None | None | Sinemet Artane Baclofen BTX to calf Valium | None None None None Yes |
| 4 | 60/F | 58 | 2 | L | Distance walking | Hip flexion with slight side to side lurch while walking. Improves with imagined walking backward while walking forward. | No | None | Mother & Father - PD | Klonopin Artane | None None |
| 5 | 61/M | 58 | 3 | R | Walking | Eversion of foot while walking on cobblestone terrain or walking down steps. Disappears while walking on flat surfaces, running, or climbing stairs. | No | None | Mother - similar movements | Sinemet | None |
| 6 | 27/F | 22 | 5 | L | Distance running | Inversion and sustained plantarflexion of the foot while walking. Movements disappeared while walking backward ,as well as imagined walking backward while walking forward. No abnormal movements when climbing stairs or during side stepping. | No | None | None | Artane | None |
| 7 | 80/M | 78 | 2 | R | Walking | Eversion of foot while walking that disappears while walking backward or sideways and climbing stairs. | No | Yes - R Wrist 'Yips' | None | Sinemet | None |
| 8 | 53/F | 49 | 4 | L | Walking | Curling of toes and inversion of foot while walking, which is also produced with foot tapping. | No | None | None | BTX Klonopin Gabapentin | Yes Yes Yes |
| 9 | 75/F | 69 | 6 | R | Walking | Hyperextension and abduction of leg. More prominent with speed walking. | No | None | None | Sinemet Ropinerole | None None |
| Mean | 49.3 | 45.6 | 3.7 |
Table 2.
Focal Task-Specific Lower Extremity Dystonia Comparative Analysis
| No. | M | F | M | F | (yrs) | R | L | Both | ||||
| Singer and Papapetropoulus4 | 4 | 1 | 3 | 1 | 3 | 59.5 | x | 0 | 4 | 0 | 0/4 | 2 |
| Schneider et al.5 | 17 | 6 | 11 | 5 | 11 | 48.2 | PD - 1 LD -2 Hand Tremor - 1 | 7 | 8 | 1 | 2/15 (arm, cervical dystonia) | NR |
| Wu and Jankovic6 | 5 | 2 | 3 | 2 | 3 | 37.4 | 0 | 1 | 4 | 0 | 0/5 | 0 |
| McKeon et al.7 | 36 | 5 | 31 | 0 | 14 | 51.1 | NR | NR | NR | NR | 0/14 | 4 |
| MSMC | 9 | 3 | 6 | 3 | 6 | 45.7 | PD - 2 LD - 1 | 5 | 4 | 0 | 1/9(yips) | 0 |
| Total | 71</emph> | 17</emph> | 54</emph> | 11</emph> | 37 | 48.38 | 13 | 20 | 1 | 6 |