References
- Grimaldi G, Manto M. Is essential tremor a Purkinjopathy? The role of the cerebellar cortex in its pathogenesis. Mov Disord. 2013;28:1759–1761. DOI: 10.1002/mds.25645
- Benito-Leon J. Essential tremor: a neurodegenerative disease? Tremor Other Hyperkinet Mov (N Y). 2014;4:252. DOI: 10.5334/tohm.227
- Bonuccelli U. Essential tremor is a neurodegenerative disease. J Neural Transm. 2012;119:1383–1387. DOI: 10.1007/s00702-012-0878-8
- Lenka A, Pandey S. Essential Tremor: Five New Things. Neurol Clin Pract. 2022;12:183–186. DOI: 10.1212/CPJ.0000000000001145
- Wagle Shukla A. Diagnosis and Treatment of Essential Tremor. Continuum (Minneap Minn). 2022;28:1333–1349. DOI: 10.1212/CON.0000000000001181
- Bermejo-Pareja F, Louis ED, Benito-Leon J. Risk of incident dementia in essential tremor: A population-based study. Mov Disord. 2007;22:1573–1580. DOI: 10.1002/mds.21553
- Thawani SP, Schupf N, Louis ED. Essential tremor is associated with dementia: prospective population-based study in New York. Neurology. 2009;73:621–625. DOI: 10.1212/WNL.0b013e3181b389f1
- Ghanem A, Berry DS, Burkes A, et al. Prevalence of and Annual Conversion Rates to Mild Cognitive Impairment and Dementia: Prospective, Longitudinal Study of an Essential Tremor Cohort. Ann Neurol. 2024;95:1193–1204. DOI: 10.1002/ana.26927
- Wainman E, Berry DS, Hernandez NC, et al. Neuropathologic Changes in People With Essential Tremor With Dementia: A Postmortem Study. Neurology. 2025;105:
e214310 . DOI: 10.1212/WNL.0000000000214310 - Saez-Calveras N, Vaquer-Alicea J, White CL
3rd , et al. Essential tremor with tau pathology features seeds indistinguishable in conformation from Alzheimer’s disease and primary age-related tauopathy. Acta Neuropathol. 2025;149:6. DOI: 10.1007/s00401-024-02843-6 - Louis ED, Ottman R. How many people in the USA have essential tremor? Deriving a population estimate based on epidemiological data. Tremor Other Hyperkinet Mov (N Y). 2014;4:259. DOI: 10.5334/tohm.198
- Talboom JS, Haberg A, De Both MD, et al. Family history of Alzheimer’s disease alters cognition and is modified by medical and genetic factors. Elife. 2019;8. DOI: 10.7554/eLife.46179
- Slooter AJ, Cruts M, Kalmijn S, et al. Risk estimates of dementia by apolipoprotein E genotypes from a population-based incidence study: the Rotterdam Study. Arch Neurol. 1998;55:964–968. DOI: 10.1001/archneur.55.7.964
- Woodruff BK, Graff-Radford NR, Ferman TJ, et al. Family history of dementia is a risk factor for Lewy body disease. Neurology. 2006;66:1949–1950. DOI: 10.1212/01.wnl.0000219812.20616.b3
- Meyers JH, Hickman R, Cristal AD, Factor-Litvak P, Cosentino S, Louis ED. More unaffected first-degree relatives of essential tremor cases have mild cognitive deficits than age-matched controls. Parkinsonism Relat Disord. 2019;61:144–150. DOI: 10.1016/j.parkreldis.2018.10.030
DOI: https://doi.org/10.5334/tohm.1289 | Journal eISSN: 2160-8288
Language: English
Page range: 58 - 58
Submitted on: Sep 2, 2026
Accepted on: Oct 10, 2026
Published on: Oct 22, 2026
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Keywords:
© 2026 Elan D. Louis, Stephanie Cosentino, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.