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Magnetic Resonance Image Guided Focused Ultrasound Thalamotomy for Essential Tremor in a Patient with an Arteriovenous Malformation Cover

Magnetic Resonance Image Guided Focused Ultrasound Thalamotomy for Essential Tremor in a Patient with an Arteriovenous Malformation

Open Access
|May 2026

References

  1. Gagliardo C, Cannella R, Filorizzo G, et al. Preoperative imaging findings in patients undergoing transcranial magnetic resonance imaging-guided focused ultrasound thalamotomy. Sci Rep. 2021;11(1):2524. Published 2021 Jan 28. DOI: 10.1038/s41598-021-82271-8
  2. Gonzalez-Quarante LH, Gonzalez-Crespo A, Arcadi A, et al. 3-T MR-guided focused ultrasound thalamotomy for tremor in patients with a cardiac pacemaker: case series and review of the literature. Neurosurg Focus. 2024;57(3):E5. DOI: 10.3171/2024.6.FOCUS24171
  3. Buch VP, McShane BJ, Beatson N, et al. Focused Ultrasound Thalamotomy with Dentato-Rubro-Thalamic Tractography in Patients with Spinal Cord Stimulators and Cardiac Pacemakers. Stereotact Funct Neurosurg. 2020;98(4):263269. DOI: 10.1159/000507031
  4. Abdullah B, Subramaniam R, Omar S, Wragg P, Ramli N, Wui A, Lee C, Yusof Y. Magnetic resonance-guided focused ultrasound surgery (MRgFUS) treatment for uterine fibroids. Biomed Imaging Interv J. 2010 Apr–Jun;6(2):e15. DOI: 10.2349/biij.6.2.e15. Epub 2010 Apr 1. PMID: 21611036. PMCID: PMC3097768.
  5. Ehdaie B, Tempany CM, Holland F, Sjoberg DD, Kibel AS, Trinh QD, Durack JC, Akin O, Vickers AJ, Scardino PT, Sperling D, Wong JYC, Yuh B, Woodrum DA, Mynderse LA, Raman SS, Pantuck AJ, Schiffman MH, McClure TD, Sonn GA, Ghanouni P. MRI-guided focused ultrasound focal therapy for patients with intermediate-risk prostate cancer: a phase 2b, multicentre study. Lancet Oncol. 2022 Jul;23(7):910918. DOI: 10.1016/S1470-2045(22)00251-0. Epub 2022 Jun 14. PMID: 35714666. PMCID: PMC9400094.
  6. Maesawa S, Nakatsubo D, Tsugawa T, et al. [Magnetic Resonance-guided Focused Ultrasound Ablation:Techniques and Neurological Applications]. No Shinkei Geka. 2021;49(4):847856. DOI: 10.11477/mf.1436204463
  7. U.S. Food and Drug Administration. Summary of Safety and Effectiveness Data (SSED): ExAblate Model 4000 Type 1.0 System (ExAblate Neuro). Premarket Approval (PMA) P150038: InSightec, Inc.; July 11, 2016.
  8. Maamary J, Peters J, Barnett Y, Jonker B, Tisch S. The feasibility of MRI guided focused ultrasound for posttraumatic tremor with prior hemicraniotomy and skull defect [abstract]. Mov Disord. 2023; 38 (suppl 1).
  9. Xu Z, Carlson C, Snell J, et al. Intracranial inertial cavitation threshold and thermal ablation lesion creation using MRI-guided 220-kHz focused ultrasound surgery: preclinical investigation. J Neurosurg. 2015;122(1):152161. DOI: 10.3171/2014.9.JNS14541
  10. Martínez-Fernández R, Pineda-Pardo JA, Natera-Villalba E, et al. Brain Bleeding Associated With Cavitation During Focused Ultrasound Ablation. Neurosurgery. 2025;97(5):12151218. DOI: 10.1227/neu.0000000000003663
  11. Giordano M, Caccavella VM, Zaed I, et al. Comparison between deep brain stimulation and magnetic resonance-guided focused ultrasound in the treatment of essential tremor: a systematic review and pooled analysis of functional outcomes. J Neurol Neurosurg Psychiatry. 2020;91(12):12701278. DOI: 10.1136/jnnp-2020-323216
  12. Sabet H, Abbas A, Salama EY, et al. Deep brain stimulation and magnetic resonance-guided focused ultrasound for essential tremor: a meta-analysis of effectiveness and safety. Neurosurg Rev. 2026;49(1):264. Published 2026 Mar 9. DOI: 10.1007/s10143-025-04076-x
  13. Martínez-Fernández R, Pineda-Pardo JA, Natera-Villalba E, et al. Brain Bleeding Associated With Cavitation During Focused Ultrasound Ablation. Neurosurgery. 2025;97(5):12151218. DOI: 10.1227/neu.0000000000003663
  14. Siu JY, Liu C, Zhou Y. High-intensity focused ultrasound ablation around the tubing. PLoS ONE. 2017;12(11): e0188206. DOI: 10.1371/journal.pone.0188206
  15. Jones J, Bolding M, Ullman H, Kaneko N, Tateshima S. Focused Ultrasound Ablation of an Arteriovenous Malformation Model. Front Neurol. 2021;12:671380. Published 2021 Jun 3. DOI: 10.3389/fneur.2021.671380
  16. Parker WE, Weidman EK, Chazen JL, et al. Magnetic resonance–guided focused ultrasound for ablation of mesial temporal epilepsy circuits: modeling and theoretical feasibility of a novel noninvasive approach. Journal of Neurosurgery JNS. 2020;133(1):6370. DOI: 10.3171/2019.4.JNS182694
  17. Jones RM, Kamps S, Huang Y, et al. Accumulated thermal dose in MRI-guided focused ultrasound for essential tremor: repeated sonications with low focal temperatures. J Neurosurg. 2019;132(6):18021809. Published 2019 May 10. DOI: 10.3171/2019.2.JNS182995
  18. Yang AI, Hitti FL, Alabi OO, et al. Patient-specific effects on sonication heating efficiency during magnetic resonance-guided focused ultrasound thalamotomy. Med Phys. 2021;48(11):65886596. DOI: 10.1002/mp.15239
  19. Chang WS, Jung HH, Zadicario E, et al. Factors associated with successful magnetic resonance-guided focused ultrasound treatment: efficiency of acoustic energy delivery through the skull. Journal of Neurosurgery JNS. 2016;124(2):411416. DOI: 10.3171/2015.3.JNS142592
  20. Thomas B, Bellini G, Lee WY, Shi Y, Mogilner A, Pourfar MH. High Intensity Focused Ultrasound - Longitudinal Data on Efficacy and Safety. Tremor Other Hyperkinet Mov (NY). 2025 May 5;15:18. DOI: 10.5334/tohm.987. PMID: 40351562. PMCID: PMC12063574.
DOI: https://doi.org/10.5334/tohm.1210 | Journal eISSN: 2160-8288
Language: English
Page range: 34 - 34
Submitted on: Mar 24, 2026
Accepted on: May 14, 2026
Published on: May 27, 2026
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2026 Tomaima Yousef, Elma A. Chowdhury, Piush Sarkar, Hooman Azmi, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.