Table 1
Baseline Demographic and Clinical Features of 90 ET Cases.
| VARIABLE | DATA |
|---|---|
| Age (years) | 77.5 ± 9.1 (range = 58–95) |
| Female sex | 51 (56.7) |
| Education (years) | 16.0 ± 2.5 |
| Family history of ET | 43 (47.8) |
| Duration of tremor (years) | 38.7 ± 21.2 (range = 2–86) |
| Has been prescribed medication for ET | 75 (83.3) |
| IT score | 0.89 ± 0.60 (range = 0–2) |
| Spiral score | 4.12 ± 1.27 (1.5–6) |
| Postural tremor score | 2.60 ± 1.34 (0–6) |
| Total Tremor Score | 23.7 ± 5.6 (range = 10.5–35) |
[i] Values represent mean ± standard deviation unless specified otherwise.
ET = essential tremor, IT = intention tremor.
Table 2
MANOVA Models Assessing Time Effects.
| CONDITION | T1 | T2 | T3 | T4 | MANOVA (TIME EFFECT) |
|---|---|---|---|---|---|
| IT score | 0.89 ± 0.60 | 0.86 ± 0.75 | 0.99 ± 0.52 | 1.16 ± 0.63 > T3 > T2 > T1 | 0.001 |
| Spiral score | 4.10 ± 1.28 | 4.34 ± 1.52 | 4.15 ± 1.12 | 4.08 ± 1.20 | 0.088 |
| Postural tremor score | 2.62 ± 1.34 | 2.98 ± 1.40 >T1 | 2.26 ± 1.47 <T2 <T1 | 2.53 ± 1.60 <T2 | < 0.001 |
[i] IT = Intention tremor, T = time.
>T3 = value significantly greater than the T3 value at p < 0.05 (paired sample-t test).
>T2 = value significantly greater than the T2 value at p < 0.05 (paired sample-t test).
>T1 = value significantly greater than the T1 value at p < 0.05 (paired sample-t test).
<T2 = value significantly less than the T2 value at p < 0.05 (paired sample-t test).
<T1 = value significantly less than the T1 value at p < 0.05 (paired sample-t test).
Table 3
Baseline Demographic and Clinical Features of ET Cases Stratified into Three Groups Values represent mean ± standard deviation unless specified otherwise.
| VARIABLE | T1 > T4a | T1 = T4a | T1 < T4a | SIGNIFICANCE |
|---|---|---|---|---|
| n | 20 | 24 | 46 | |
| Age (years) | 77.0 ± 10.4 | 78.4 ± 8.7 | 77.3 ± 9.0 | p = 0.86b |
| Female sex | 10 (50.0) | 13 (54.2) | 28 (60.9) | p = 0.69c |
| Family history of ET | 8 (40.0) | 11 (45.8) | 24 (52.2) | p = 0.65c |
| Duration of tremor (years) | 34.2 ± 23.5 | 38.7 ± 20.2 | 40.6 ± 20.9 | p = 0.54b |
| Has been prescribed medication for ET | 15 (75.0) | 21 (87.5) | 39 (84.8) | p = 0.50c |
| Total Tremor Score | 24.3 ± 6.0 | 23.9 ± 5.8 | 23.4 ± 5.4 | p = 0.84b |
[i] ET = essential tremor.
a T1 >T4 (IT score at T1 > IT score at T4), T1 = T4 (IT score at T1 = IT score at T4), T1 < T4 (IT score at T1 < IT score at T4).
b One-way ANOVA.
c Chi square test.