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Understanding Tremor in Multiple Sclerosis: Prevalence, Pathological Anatomy, and Pharmacological and Surgical Approaches to Treatment Cover

Understanding Tremor in Multiple Sclerosis: Prevalence, Pathological Anatomy, and Pharmacological and Surgical Approaches to Treatment

Open Access
|Sep 2012

Figures & Tables

Table 1.

Main Prevalence Studies of Tremor in Multiple Sclerosis

ReferenceSamplePrevalence
Weinshenker et al.9259 patients selected from a regional multiple sclerosis clinic (Ontario, USA)33%
Alusi et al.10100 patients randomly selected from a London multiple sclerosis unit58% (Severe in 15%)
Pittock et al.11200 patients selected from a community-based study (Minnesota, USA)25.5% (Severe in 3%)
Table 2.

Treatment Options for Multiple Sclerosis Tremor

Surgical treatment
Deep brain stimulation thalamotomyBoth are comparable procedures for tremor suppression
Pharmacological agents
Insufficient evidence to support or refute the efficacy. Possibly effective
Topiramate
Riluzole
Rituximab
Isoniazid
Carbamazepine
Gluthetimide
Intratecal baclofen
Botulinum toxin type A
They probably do not reduce multiple sclerosis tremor
Levetiracetam
Propanolol
Ondansetron
It should not be considered for treatment of multiple sclerosis tremor
Cannabis
DOI: https://doi.org/10.5334/tohm.109 | Journal eISSN: 2160-8288
Language: English
Submitted on: Jun 2, 2012
Accepted on: Jul 6, 2012
Published on: Sep 14, 2012
Published by: Columbia University Libraries/Information Services
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2012 Andrés Labiano-Fontcuberta, Julián Benito-León, published by Columbia University Libraries/Information Services
This work is licensed under the Creative Commons License.