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The Effect of Physical Activity on Arterial Stiffness, Inflammation and Lipoproteins among 30–65-Year-Old Men Cover

The Effect of Physical Activity on Arterial Stiffness, Inflammation and Lipoproteins among 30–65-Year-Old Men

Open Access
|Apr 2023

Figures & Tables

paah-7-1-230-g1.png
Figure 1

The study inclusion/exclusion flowchart. MetS = Metabolic syndrome PA = physical activity.

Table 1

Baseline characteristics.

ACTIVITY GROUPGLYCEMIC STATUS
METS n = 120NON-METS n = 67
SEDENTARYN = 66MPA n = 36HPA n = 18MPA n = 23HPA n = 44
Age, years49.5 ± 8.152.0 ± 8.051.8 ± 8.552.9 ± 5.652.3 ± 8.9
Physical activity, kcal/day24.1 ± 32.1175.5 ± 42.4529.6 ± 178.1209.0 ± 65.0604.6 ± 262.8
Waist circumference, cm113.0 ± 11.0113.1 ± 12.6113.9 ± 17.390.0 ± 7.489.4 ± 7.1
BMI, kg/m232.0 ± 4.631.9 ± 5.431.8 ± 5.624.1 ± 2.224.5 ± 2.2
Medication
  • aspirin, n (%)

15(28%)10 (28%)4 (22%)3 (13%)2 (5%)
  • beta-blockers, n (%)

24 (36%)14 (39%)4 (22%)1 (4%)0 (0%)
  • ACE-inhibitors, n (%)

11 (17%)6 (17%)3 (17%)1 (4%)2 (5%)
  • ARBs, n (%)

19 (29%)7 (19%)0 (0%)0 (0%)1 (2%)
  • statins, n (%)

21 (32%)9 (25%)5 (28%)4 (17%)4 (9%)
  • glucose-lowering drugs, n (%)

13 (20%)3 (8%)2 (11%)0 (0%)0 (0%)
Smoking
  • current, n (%)

19 (29%)4 (11%)2 (11%)1 (4%)0 (0%)
  • former, n (%)

29 (44%)18 (50%)10 (56%)6 (26%)19 (43%)
  • never, n (%)

18 (27%)14 (39%)6 (33%)16 (70%)25 (57%)
  • Pack-years in smokers

17.9 ± 15.917.1 ± 11.913.3 ± 11.44.1 ± 3.09.0 ± 8.6
  • SBP, mmHg

140.1 ± 12.6135.1 ± 12.6143.8 ± 18.6129.6 ± 15.7129.4 ± 10.8
  • DBP, mmHg

82.8 ± 7.879.7 ± 6.085.5 ± 11.675.6 ± 8.775.5 ± 5.7

[i] The values are presented as number (%) and mean ± standard deviation. MetS: Metabolic Syndrome BMI: Body mass index ACE: Angiotensin-converting enzyme ARB: Angiotensin II receptor blockers SBP: Systolic blood pressure DBP: Diastolic blood pressure MPA: Moderate physical activity group HPA: High physical activity group.

paah-7-1-230-g2.png
Figure 2

Laboratory results according to metabolic and physical activity status.

MetS: Metabolic syndrome MPA: Moderate physical activity group HPA: High physical activity group hs-CRP: High-sensitivity C-reactive protein HDL-C: High-density lipoprotein cholesterol LDL: Low-density lipoprotein cholesterol TG: Triglycerides HbA1c: Glycated hemoglobin.

paah-7-1-230-g3.png
Figure 3

Resting heart rate and arterial elasticity according to metabolic and physical activity status.

MetS: Metabolic syndrome MPA: Moderate physical activity group HPA: High physical activity group RHR: Resting heart rate C1: Capacitive elasticity of large arteries C2: Reflective elasticity of small arteries.

Table 2

Comparison of MetS subjects in the HPA group vs. non-MetS subjects in the MPA group

METS HPANON-METS MPAP-VALUE
hs-CRP (mg/L)1.1 (2.2)0.8 (0.5)0.003
HDL-C (mmol/L)1.2 ± 0.21.6 ± 0.30.003
LDL-C (mmol(L)3.2 ± 1.13.3 ± 0.8NS
TG (mmol/L)2.9 ± 3.21.1 ± 0.4<0.001
RHR (bpm)66.0 ± 10.557.9 ± 10.70.009
C1 (ml/mmHg × 10)16.6 ± 4.717.6 ± 5.4NS
C2 (ml/mmHg × 100)6.6 ± 3.06.3 ± 3.1NS
HbA1c (mmol/mol)43.3 ± 14.438.1 ± 2.1NS

[i] MPA: Moderate physical activity group HPA: High physical activity group hs-CRP: High-sensitivity C-reactive protein HDL-C: High-density lipoprotein cholesterol LDL: Low-density lipoprotein cholesterol TG: Triglycerides RHR: Resting heart rate C1: capacitive elasticity of large arteries C2: reflective elasticity of small arteries HbA1c: Glycated hemoglobin.

DOI: https://doi.org/10.5334/paah.230 | Journal eISSN: 2515-2270
Language: English
Submitted on: Nov 6, 2022
|
Accepted on: Mar 23, 2023
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Published on: Apr 28, 2023
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2023 Harri J. Saarinen, Hanna Pohjantähti-Maaroos, Riitta Antikainen, Jorma T. Lahtela, Ari Palomäki, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.