Table 1
P values of independent-samples T-Tests comparing average ΔΔCt of the CF rested group to the WT rested group. Statistically significant (p ≤ .008) increases are highlighted in dark gray.
| Tissue Type | Clock | Bmal1 | Per1 | Per2 | Cry1 | Cry2 |
|---|---|---|---|---|---|---|
| Brain | <.001 | .568 | .467 | .795 | .165 | <.001 |
| Jejunum | .008 | .004 | .108 | .419 | .072 | .233 |
| Adipose | .232 | .314 | .712 | .969 | .214 | .169 |
| Colon | .936 | .054 | .603 | .245 | .669 | .363 |
| Lung | .642 | .824 | .804 | .915 | .933 | .626 |
| Skeletal Muscle | .294 | .681 | .282 | .405 | .101 | .07 |
Figure 1
Fold change of the WT rested group vs. the CF rested group in each measured transcript grouped by tissue. Bars represent gene expression of the CF rested group, whereas the WT rested group is represented by 1 on the Y axis. Asterisks indicate statistical significance (p ≤ 0.008).
Table 2
P values of independent-samples T-Tests comparing average ΔΔCt of the WT sleep deprived group to the CF sleep deprived group. Statistically significant (p ≤ .008) increases are highlighted in dark gray and decreases in light gray. Asterisks indicate statistical significance (p ≤ 0.008).
| Tissue Type | Clock | Bmal1 | Per1 | Per2 | Cry1 | Cry2 |
|---|---|---|---|---|---|---|
| Brain | <.001 | <.001 | .046 | <.001 | .036 | .193 |
| Jejunum | .018 | .010 | .017 | .048 | .057 | .306 |
| Adipose | .067 | .611 | .025 | .081 | <.001 | <.001 |
| Colon | .208 | .848 | .101 | .171 | .007 | .065 |
| Lung | .023 | .372 | .005 | .001 | .911 | .918 |
| Skeletal Muscle | .137 | .069 | .126 | .204 | .016 | .077 |
Figure 2
Fold change of the WT sleep deprived group vs. the CF sleep deprived group in each measured transcript grouped by tissue. Bars represent gene expression of the CF sleep deprived group, whereas the WT sleep deprived group is represented by 1 on the Y axis. Asterisks indicate statistical significance (p ≤ 0.008).
Table 3
P values of independent-samples T-Tests comparing average ΔΔCt of the WT rested group to the WT sleep deprived group. Statistically significant (p ≤ .008) increases are highlighted in dark gray.
| Tissue Type | Clock | Bmal1 | Per1 | Per2 | Cry1 | Cry2 |
|---|---|---|---|---|---|---|
| Brain | .962 | .717 | .855 | .487 | .011 | .005 |
| Jejunum | .860 | .653 | .323 | .716 | .381 | .285 |
| Adipose | .021 | .047 | .016 | .002 | .005 | .822 |
| Colon | .831 | .581 | .454 | .916 | .005 | .693 |
| Lung | .072 | .075 | .129 | .111 | .004 | .006 |
| Skeletal Muscle | .960 | .067 | .798 | .443 | <.001 | <.001 |
Figure 3
Fold change of the WT rested group vs. the WT sleep deprived group in each measured transcript grouped by tissue. Bars represent gene expression of the WT sleep deprived group, whereas the WT rested group is represented by 1 on the Y axis. Asterisks indicate statistical significance (p ≤ 0.008).
Table 4
P values of independent-samples T-Tests comparing average ΔΔCt of the CF rested group to the CF sleep deprived group. Statistically significant (p ≤ .008) increases are highlighted in dark gray and decreases in light gray.
| Tissue Type | Clock | Bmal1 | Per1 | Per2 | Cry1 | Cry2 |
|---|---|---|---|---|---|---|
| Brain | .010 | .002 | .077 | .041 | .285 | .112 |
| Jejunum | .632 | .965 | .202 | .473 | .409 | .28 |
| Adipose | .095 | .162 | .005 | .014 | .167 | .001 |
| Colon | .678 | .125 | .107 | .103 | .908 | .007 |
| Lung | <.001 | .003 | <.001 | .008 | .056 | .003 |
| Skeletal Muscle | .076 | .934 | .064 | .036 | .472 | .431 |
Figure 4
Fold change of the CF rested group vs. the CF sleep deprived group in each measured transcript grouped by tissue. Bars represent gene expression of the CF sleep deprived group, whereas the CF rested group is represented by 1 on the Y axis. Asterisks indicate statistical significance (p ≤ 0.008).