Have a personal or library account? Click to login
Safety, Efficacy, and Intermediate‑Term Outcomes of CT‑Guided Cryoablation of T1 Renal Cell Carcinoma: A Retrospective Single‑Center Study Cover

Safety, Efficacy, and Intermediate‑Term Outcomes of CT‑Guided Cryoablation of T1 Renal Cell Carcinoma: A Retrospective Single‑Center Study

Open Access
|Mar 2026

References

  1. Ljungberg B, Albiges L, Abu‑Ghanem Y, et al. European association of urology guidelines on renal cell carcinoma: The 2022 Update. Eur Urol. 2022;82:399410. 10.1016/j.eururo.2022.03.006.
  2. Crestani A, Rossanese M, Calandriello M, Sioletic S, Giannarini G, Ficarra V. Introduction to small renal tumours and prognostic indicators. Int J Surg. 2016;36:495503. 10.1016/j.ijsu.2016.03.038.
  3. Welch HG, Kramer BS, Black WC. Epidemiologic signatures in cancer. N Engl J Med. 2019;381:13781386. 10.1056/NEJMsr1905447.
  4. Campbell SC, Clark PE, Chang SS, Karam JA, Souter L, Uzzo RG. Renal mass and localized renal cancer: Evaluation, management, and follow‑up: AUA guideline: Part I. J Urol. 2021;206:199208. 10.1097/JU.0000000000001911.
  5. Tanagho YS, Kaouk JH, Allaf ME, et al. Perioperative complications of robot‑assisted partial nephrectomy: Analysis of 886 patients at 5 United States centers. Urology. 2013;81:573579. 10.1016/j.urology.2012.10.067.
  6. Shuch B, Linehan WM, Bratslavsky G. Repeat partial nephrectomy: Surgical, functional and oncological outcomes. Curr Opin Urol. 2011;21:368375. 10.1097/MOU.0b013e32834964ea.
  7. El Dib R, Touma NJ, Kapoor A. Cryoablation vs radiofrequency ablation for the treatment of renal cell carcinoma: A meta‑analysis of case series studies. BJU Int. 2012;110:510516. 10.1111/j.1464-410X.2011.10885.x.
  8. Garnon J, Van Strijen MJ, Nielsen TK, et al. Safety of percutaneous renal cryoablation: An international multicentre experience from the EuRECA retrospective percutaneous database. Eur Radiol. 2019;29:62936299. 10.1007/s00330-019-06191-y.
  9. Rodriguez R, Cizman Z, Hong K, Koliatsos A, Georgiades C. Prospective analysis of the safety and efficacy of percutaneous cryoablation for pT1NxMx biopsy‑proven renal cell carcinoma. Cardiovasc Intervent Radiol. 2011;34:573578. 10.1007/s00270-010-9934-7.
  10. Gobara H, Hiraki T, Iguchi T, et al. Oncologic outcomes and safety of percutaneous cryoablation for biopsy‑proven renal cell carcinoma up to 4 cm in diameter: A prospective observational study. Int J Clin Oncol. 2021;26:562568. 10.1007/s10147-020-01825-4.
  11. Cernic S, Marrocchio C, Ciabattoni R, et al. Percutaneous CT‑guided renal cryoablation: Technical aspects, safety, and long‑term oncological outcomes in a single center. Medicina (Kaunas). 2021;57:291. 10.3390/medicina57030291.
  12. Georgiades CS, Hong K, Bizzell C, Geschwind JF, Rodriguez R. Safety and efficacy of CT‑guided percutaneous cryoablation for renal cell carcinoma. J Vasc Interv Radiol. 2008;19:13021310. 10.1016/j.jvir.2008.05.015.
  13. Georgiades CS, Rodriguez R. Efficacy and safety of percutaneous cryoablation for stage 1A/B renal cell carcinoma: Results of a prospective, single‑arm, 5‑year study. Cardiovasc Intervent Radiol. 2014;37:14941499. 10.1007/s00270-013-0831-8.
  14. Katsanos K, Mailli L, Krokidis M, McGrath A, Sabharwal T, Adam A. Systematic review and meta‑analysis of thermal ablation versus surgical nephrectomy for small renal tumours. Cardiovasc Intervent Radiol. 2014;37:427437. 10.1007/s00270-014-0846-9.
  15. Pierorazio PM, Johnson MH, Patel HD, et al. Management of renal masses and localized renal cancer: Systematic review and meta‑analysis. J Urol. 2016;196:989999. 10.1016/j.juro.2016.04.081.
  16. Spiliopoulos S, Marzoug A, Ra H, Ragupathy SKA. Long‑term outcomes of CT‑guided percutaneous cryoablation of T1a and T1b renal cell carcinoma. Diagn Interven Radiol. 2021;27:524528. 10.5152/dir.2021.20342.
  17. Breen DJ, King AJ, Patel N, Lockyer R, Hayes M. Image‑guided cryoablation for sporadic renal cell carcinoma: Three‑ and 5‑year outcomes in 220 patients with biopsy‑proven renal cell carcinoma. Radiology. 2018;289:554561. 10.1148/radiol.2018180249.
  18. Ahmed M, Solbiati L, Brace CL, et al. Image‑guided tumor ablation: Standardization of terminology and reporting criteria‑a 10‑year update. Radiology. 2014;273:241260. 10.1148/radiol.14132958.
  19. Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 Clinical practice Guideline for the evaluation and management of chronic kidney disease. Kidney Int Suppl. 2013;3(1):1163. https://kdigo.org/wp-content/uploads/2017/02/KDIGO_2012_CKD_GL.pdf.
  20. Clavien PA, Sanabria JR, Strasberg SM. Proposed classification of complications of surgery with examples of utility in cholecystectomy. Surgery. 1992;111:518526.
  21. Dindo D, Demartines N, Clavien PA. Classification of surgical complications: A new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240:205213. 10.1097/01.sla.0000133083.54934.ae.
  22. Uhlig J, Strauss A, Rücker G, et al. Partial nephrectomy versus ablative techniques for small renal masses: A systematic review and network meta‑analysis. Eur Radiol. 2019;29:12931307. 10.1007/s00330-018-5660-3.
  23. Auer T, Uluk Y, Grasso R, et al. Image‑guided percutaneous ablative treatments for renal cell carcinoma. Eur Radiol. 2025;35:53245336. 10.1007/s00330-025-11480-w.
  24. Hegg RM, Schmit GD, Boorjian SA, et al. Percutaneous renal cryoablation after partial nephrectomy: Technical feasibility, complications and outcomes. J Urol. 2013;189:12431248. 10.1016/j.juro.2012.10.066.
  25. Stacul F, Sachs C, Giudici F, et al. Cryoablation of renal tumors: Long‑term follow‑up from a multicenter experience. Abdom Radiol (NY). 2021;46:44764488. 10.1007/s00261-021-03082-z.
DOI: https://doi.org/10.5334/jbsr.3919 | Journal eISSN: 2514-8281
Language: English
Submitted on: Mar 6, 2025
|
Accepted on: Feb 19, 2026
|
Published on: Mar 11, 2026
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2026 Laura Frenoy, Pieter‑Jan Buyck, Lawrence Bonne, Ben Van Cleynenbreugel, Maarten Albersen, Geert Maleux, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.