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Can T1W and T2W Dixon Sequences Replace the Standard MRI Protocol in Diagnosing Sacroiliitis? Cover

Can T1W and T2W Dixon Sequences Replace the Standard MRI Protocol in Diagnosing Sacroiliitis?

Open Access
|Dec 2024

Figures & Tables

Table 1

Magnetic resonance imaging acquisition parameters for the sacroiliac joints. TR: time to repeat, TE: time to echo.

PARAMETERSSECTION THICKNESS (MM)FIELD OF VIEW (MM × MM)MATRIXTR/TEACQUISITION TIME (MIN:S)
T1W3270265 × 448402/222:44
T2W‑FS3270216 × 3203220/721:41
T1W‑Dixon3250195 × 320607/102:11
T2W‑Dixon3270202 × 3204620/813:11
Table 2

Characteristics of the our study sample according to standard MRI protocol findings.

STANDARD MRI PROTOCOL FINDINGSNUMBER OF CASESAGE RANGE (YEARS)MEAN AGE (YEARS)GENDER (FEMALE/MALE)
Positive active sacroiliitis findings635–4539.336/0
Positive chronic sacroiliitis findings1418–4733.787/7
Active on chronic sacroiliitis findings2921–5036.0622/7
No active or chronic sacroiliitis findings5818–4836.3738/20
Total10718–5036.1273/34
Table 3

The number of sacroiliac joints with positive findings on MRI sequences.

MRI FINDINGST2W‑FST1WT1W DIXON FOT1W DIXON IPT1W DIXON OPT2W DIXON WOT2W DIXON FOT2W DIXON IPT2W DIXON OP
BME5657
Erosion87858571828068
Subchondral sclerosis4321225222015
PFD23212120212121
Ankylosis5444444
Backfill7640355
jbsr-108-1-3658-g1.png
Figure 1

Coronal T2W‑FS (a) and T2W Dixon WO (b) images show bone marrow edema (circles) in both sacroiliac joints on the right sacral and iliac side and on the left iliac side in a 48‑year‑old female patient. Bone marrow edema signals are brighter on T2W Dixon WO images (b).

jbsr-108-1-3658-g2.png
Figure 2

A 33‑year‑old female patient with iliac side sclerosis (ovoid circle), sacral side periarticular fat deposits (star) and iliac‑sacral facial erosions (curved arrow) in both sacroiliac joints marked on a T1W images (a). These findings can also be seen in T2W Dixon IP (b), T2W Dixon OP (c), T2W Dixon FO (d), T1W Dixon IP (e), T1W Dixon OP (f) and T1W Dixon FO (g) images.

jbsr-108-1-3658-g3.png
Figure 3

A 34‑year‑old male patient with ankylosis (arrow) in both sacroiliac joints on a T1W image (a) (arrows). Ankylosis can be easily seen in the T2W Dixon IP (b), T2W Dixon OP (c), T2W Dixon FO (d), T1W Dixon IP (e), T1W Dixon OP (f) and T1W Dixon FO (g) images shown in the figure.

jbsr-108-1-3658-g4.png
Figure 4

A 36‑year‑old male patient with backfill (circle) in the right sacroiliac joint on a T1W images (a). T2W Dixon IP (b), T2W Dixon OP (c), T2W Dixon FO (d), T1W Dixon IP (e), T1W Dixon OP (f) and T1W Dixon FO (g) images are also shown in the figure.

Table 4

Interobserver agreement assessment values at 214 SIJs for signs of active and chronic sacroiliitis.

KP
BME, T2W‑FS0.930.01
BME, T2W Dixon0.910.01
Erosion, T1W0.840.01
Sclerosis, T1W0.720.01
PFD, T1W0.910.01
Backfill, T1W0.530.01
Ankylosis, T1W0.890.01
Erosion, T1W Dixon0.810.01
Sclerosis, T1W Dixon0.570.01
PFD, T1W Dixon0.790.01
Backfill, T1W Dixon0.660.01
Ankylosis, T1W Dixon0.890.01
Erosion, T2W Dixon0.780.01
Sclerosis, T2W Dixon0.500.01
PFD, T2W Dixon0.840.01
Backfill, T2W Dixon0.800.01
Ankylosis, T2W Dixon1.00.01
Table 5

The diagnostic performance of T1W and T2W Dixon sequences compared with the standard MRI protocol. PPV, positive predictive value; NPV, negative predictive value.

MRI FINDINGSSENSITIVITY (%)SPECIFICITY (%)PPV (%)NPV (%)ACCURACY (%)
T1W DixonErosion91.9596.8595.2494.6294.86
Subchondral sclerosis44.4498.2289.9686.9186.92
PFD86.9699.4895.2498.4598.13
Backfill57.14100.00100.0098.5798.57
Ankylosis80.0099.5280.099.5299.07
T2W DixonBME98.2599.3698.2599.3699.07
Erosion88.8999.1998.7792.4894.86
Subchondral sclerosis37.7897.6380.9585.4985.05
PFD86.9698.9590.9198.4497.66
Backfill57.14100.00100.0098.5798.57
Ankylosis80.00100.00100.0099.5299.53
DOI: https://doi.org/10.5334/jbsr.3658 | Journal eISSN: 2514-8281
Language: English
Submitted on: May 28, 2024
Accepted on: Nov 22, 2024
Published on: Dec 12, 2024
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2024 Nur Betül Karatoprak, Zeynep Maraş Özdemir, Sinan Karatoprak, Ayşegül Sağır Kahraman, Leyla Karaca, Servet Yolbaş, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.