Table 1
Demographic data and presenting symptoms of patients with olfactory neuroblastoma
| NO. (%) | |
|---|---|
| Number of patients | 58 (100) |
| Age range Mean age (SD) (yr) | 23–84 50.61 (±15.6) |
| Sex Male Female | 35 (60.3) 23 (39.7) |
| Imaging studies CT MRI | 50 36 |
| Presenting symptoms Nasal obstruction Epistaxis Anosmia Rhinorrhea Proptosis Eye pain | 25 (43.1) 19 (32.8) 5 (8.6) 4 (6.9) 2 (3.4) 3 (5.2) |
Table 2
Location, epicenter, and extension of olfactory neuroblastoma
| LOCATION AND EXTENSION | NO. (%) |
|---|---|
| Side (nasal cavity) Right Left Both Midline | 27 (46.6) 27 (46.6) 3 (5.2) 1 (1.7) |
| Epicenter Superior Other – Middle – Sphenoid sinus invade sella turcica | 50 (86.2) 8 (13.8) 7 (12.1) 1 (1.7) |
| Extension Frontal sinus Ethmoid sinus Maxillary sinus Sphenoid sinus Intra-orbit Intra-cranium | 34 (58.6) 50 (86.2) 24 (41.4) 30 (51.7) 26 (44.8) 44 (75.9) |
Figure 1
Typical location of olfactory neuroblastoma (ONB), shown in a 70-year-old woman presenting with anosmia. Contrast-enhanced computed tomography (CT) images showed ONB at the superior part of both nasal cavities with bilateral ethmoid sinuses and intracranial extension (A-B). Brain CT performed 4 years prior due to headache (C-D) showed soft tissue in the slightly expanded left olfactory recess, most likely representing a small ONB that went unrecognized at that time.
Figure 2
Atypical location of olfactory neuroblastoma in a 36-year-old woman presenting with nasal obstruction for 6 months. Contrast-enhanced T1-weighted imaging with fat suppression (A-B) and contrast-enhanced computed tomography (C-D) showed an enhanced mass with an epicenter at the middle part of left nasal cavity.
Figure 3
Atypical location of olfactory neuroblastoma in a 63-year-old woman presenting with epistaxis for 5 days. Contrast-enhanced T1-weighted imaging with fat suppression (A-C) and contrast-enhanced computed tomography (D-F) showed an enhanced mass within both sphenoid sinuses, slightly invading the sellar turcica.