Figure 1
Flowchart of the patient selection.
Table 1
Baseline characteristics of all patients.
| ALL | |
|---|---|
| Number of patients | 38 (100%) |
| Age, years (median, IQR) | 75 (66–86) |
| Female (%) | 29 (76%) |
| Medical History | |
| High Blood Pressure (%) | 33 (87%) |
| Diabetes (%) | 9 (24%) |
| Hyperlipidemia (%) | 18 (47%) |
| Weight (kg) (median, IQR) | 75 (65–94) |
| Antiplatelets (%) | 12 (32%) |
| Anticoagulants (%) | 7 (18%) |
| Current Smoking (%) | 6 (16%) |
| Pre-stroke mRS of 0–1 (%) | 36 (95%) |
| Clinical Presentation | |
| Heart rate (bpm) (median, IQR) | 76 (68–88) |
| Systolic Blood Pressure (mmHg) (median, IQR) | 146 (125–170) |
| Diastolic Blood Pressure (mmHg) (median, IQR) | 80 (75–85) |
| Temperature (°C) (median, IQR) | 36.9 (36.4–37.2) |
| Baseline NIHSS (median, IQR) | 10 (8–15) |
| IVT (%) | 26 (68%) |
| Times | |
| Time Onset to Puncture in min (median, IQR) | 210 (166–296) |
| Unknown Onset (%) | 10 (26%) |
| Occlusion | |
| M2 (%) | 27 (71%) |
| M3 (%) | 11 (29%) |
| Left Side (%) | 20 (53%) |
| Imaging | |
| Baseline infarct volume, mL (median, IQR) | 0.3 (0.3–6.8) |
| TMax > 4 sec volume, mL (median, IQR) | 102 (73–126) |
| TMax > 6 sec volume, mL (median, IQR) | 50 (34–76) |
| TMax > 8 sec volume, mL (median, IQR) | 25 (10–48) |
| TMax > 10 sec volume, mL (median, IQR) | 12.5 (0.3–37) |
| Mismatch volume, mL (median, IQR) | 43.9 (30.2–58.9) |
| Mismatch ratio (median, IQR) | 295 (7–488) |
| Etiology | |
| Atherosclerosis (%) | 9 (24%) |
| Cardio-embolic (%) | 28 (74%) |
| Unknown (%) | 1 (2%) |
[i] * Continuous variables are reported as median (inter-quartile range), categorical variables as percentages.
Table 2
Procedural characteristics and clinical outcomes.
| ALL | |
|---|---|
| Number of patients | 38 (100%) |
| Mechanical Thrombectomy | |
| Admission Mothership (%) | 20 (53%) |
| Type of anesthesia | |
| General Anesthesia (GA) (%) | 37 (97%) |
| Conscious Sedation then GA (%) | 1 (3%) |
| Technique | |
| Contact Aspiration (%) | 13 (34%) |
| Stent-retriever (%) | 6 (16%) |
| Combined technique (%) | 19 (50%) |
| Number of Passes (median, IQR) | 2 (1–3) |
| Procedural Complication (%) | 0 (0%) |
| Times | |
| Time Puncture to Recanalization in min (median, IQR) | 30 (20–55) |
| Time Onset to Recanalization in min (median, IQR) | 242 (191–326) |
| Early Outcomes | |
| Day 1 NIHSS (median, IQR) | 4 (1–7) |
| NIHSS Shift (median, IQR) | –3 (–9 to –1) |
| Day 1 Hemorrhagic Transformation (%) | 6 (25%) |
| ECASS PH-Type (%) | 2 (7%) |
| Final infarct volume, mL (median, IQR) | 8.4 (5.2–44.4) |
| Infarct volume progression, mL (median, IQR) | 7.2 (4.3–29.1) |
| Long-Term (3 months) Outcomes | |
| mRS 0–1 (%) | 18 (47%) |
| mRS 0–2 (%) | 23 (61%) |
| Mortality (%) | 2 (5%) |
[i] * Continuous variables are reported as median (inter-quartile range), categorical variables as percentages.
Figure 2
Association of baseline volume of severely hypoperfused brain tissue (TMax > 10 sec; mL) and final infarct volume (mL).
Figure 3
Association of baseline volume of severely hypoperfused brain tissue (TMax > 10 sec; mL) and infarct volume progression (mL).
Figure 4
Association of baseline volume of severely hypoperfused brain tissue (TMax > 10 sec; mL) and the probability of good clinical outcome at 3 months (mRS 0-2).