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Impact of Superselective Renal Artery Embolization on Renal Function and Blood Pressure Cover

Impact of Superselective Renal Artery Embolization on Renal Function and Blood Pressure

Open Access
|Nov 2020

Figures & Tables

jbsr-104-1-2223-g1.png
Figure 1

Study flow diagram.

jbsr-104-1-2223-g2.jpg
Figure 2

A 54-year-old man presenting with persistent hematuria after percutaneous nephrolithotomy. (a) An initial left renal angiogram shows a small pseudoaneurysm (black arrow) at arcuate branch of posterior segmental artery. (b) Superselective embolization of feeding artery using coaxial microcatheter system and a microcoil. (c) Postprocedural angiogram demonstrates complete devascularization of pseudoaneurysm.

jbsr-104-1-2223-g3.jpg
Figure 3

A 49-year-old woman presenting with acute left flank pain without trauma history. (a) An initial left renal angiogram reveals a huge pseudoaneurysm (black arrow) and contrast extravasation at proximal segment of anterior division. (b) Superselective embolization of anterior division using coaxial microcatheter system and detachable microcoils. (c) Complete cessation of active bleeding on final angiogram with preserved flow of posterior division.

Table 1

Baseline characteristics of the whole study population.

CharacteristicsTotalGroup AGroup Bp-value
(N = 48)(n = 25)(n = 23)
Age48.40 ± 17.1449.04 ± 17.8247.70 ± 16.740.789
Sex (male)29 (60.4%)15 (60%)14 (60.9%)>0.99
DM9 (18.8%)6 (24%)3 (13%)0.466
SBP123.12 ± 17.03123.20 ± 14.92123.04 ± 19.410.545
DBP74.79 ± 9.2274.80 ± 8.2374.78 ± 10.390.861
eGFR81.84 ± 41.6678.09 ± 42.8185.92 ± 40.930.726
CV/MACD0.37 ± 0.340.35 ± 0.330.40 ± 0.360.243

[i] DM: diabetes mellitus, SBP: systolic blood pressure, DBP: diastolic blood pressure.

Table 2

Indications for the procedure and embolic materials used.

IndicationsNumber of procedures
Aneurysm1
Angiomyolipoma17
Arteriovenous malformation2
Iatrogenic injury17
Spontaneous kidney rupture6
Traumatic injury5
Embolic materialNumber of procedures
Coil21
Polyvinyl alcohol particles15
N-butyl-2-cyanoacrylate2
Multiple agents10
Table 3

Pre- and postprocedural eGFR and blood pressure.

TotalGroup AGroup Bp-value
(N = 48)(n = 25)(n = 23)
Postprocedural AKI
Incidence7 (14.6%)1 (4%)6 (26.1%)0.044
eGFR (mL/min/1.73 m2)
Baseline81.84 ± 41.6678.09 ± 42.8185.92 ± 40.930.726
Postprocedure77.14 ± 36.9077.54 ± 39.5276.70 ± 34.700.549
Mean difference–4.70 ± 17.57–0.55 ± 16.98–9.22 ± 17.450.089
p-value0.0300.8720.019
Postprocedural HTN
Incidence3 (6.3%)0 (0%)3 (13%)0.102
SBP (mmHg)
Baseline123.12 ± 17.03123.20 ± 14.92123.04 ± 19.410.545
Postprocedure123.31 ± 16.44122.84 ± 17.49123.83 ± 15.600.837
Mean difference0.19 ± 11.79–0.36 ± 10.050.78 ± 13.640.751
p-value0.9130.6610.786
DBP (mmHg)
Baseline74.79 ± 9.2274.80 ± 8.2374.78 ± 10.390.861
Postprocedure74.67 ± 11.1874.92 ± 11.2274.39 ± 11.390.915
Mean difference–0.12 ± 10.920.12 ± 8.86–0.39 ± 12.990.658
p-value0.7350.7240.887

[i] SBP: systolic blood pressure, DBP: diastolic blood pressure.

Table 4

The logistic regression model for risk factors of AKI.

VariablesUnivariable analysisMultivariable analysis
OR95% CIp-valueOR95% CIp-valueVIF
Age0.980.94–1.030.433
Sex (male)4.820.83–28.090.0815.500.45–67.140.1821.17
DM4.380.78–24.660.094
HTN6.821.15–40.410.035
CKD12.141.95–75.730.00835.672.22–572.500.0121.58
Embolization extent2.140.93–76.890.05848.531.79–1318.570.0211.75
CV/MACD15.511.86–129.680.011
jbsr-104-1-2223-g4.png
Figure 4

ROC curve for the multivariable logistic regression analysis.

DOI: https://doi.org/10.5334/jbsr.2223 | Journal eISSN: 2514-8281
Language: English
Submitted on: Jul 1, 2020
Accepted on: Oct 19, 2020
Published on: Nov 6, 2020
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2020 Hyoung Nam Lee, Seung Boo Yang, Dong Erk Goo, Yong Jae Kim, Woong Hee Lee, Dongho Hyun, Nam Hun Heo, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.