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Abstract

Background: INTERASPIRE was an observational study of patients with coronary heart disease (CHD) from 88 hospitals in 14 countries across all six WHO regions. The objective was to describe the proportions of patients referred to and attending cardiac rehabilitation (CR) programmes and to compare lifestyle and risk factor target achievement according to participation in a CR programme.

Methods: Patients 18–80 years of age, with a first or recurrent coronary hospitalisation (acute coronary syndrome and/or revascularisation procedure) were identified and invited to an interview and examination, between six months and two years after the index hospitalisation.

Results: Overall, 4,548 (21.1% female) patients were interviewed a median of 1.05 (interquartile range 0.76–1.45) years after hospitalization. Of those patients, 34.4% reported having been advised to participate in a CR programme, though the percentage varied widely by country, from 4.0% in Kenya to 69.6% in Poland. Among patients advised to participate in CR, 57.1% participated in ≥50% of all sessions, 15.4% participated in <50% of the sessions, and 27.4% did not participate at all. Only 19.6% of all patients recruited to the study attended ≥50% of sessions. Content of programmes reported by patients also varied enormously between countries. Low education level, elective PCI, or unstable angina as recruiting events were associated with lower attendance rates. Attendance at ≥50% of all CR sessions was associated with a lower prevalence of persistent smoking and physical inactivity, better control of blood pressure and LDL-cholesterol, and a higher use of cardioprotective medications.

Conclusions: INTERASPIRE provides a standardised international picture of CR provision and attendance in patients with CHD. Despite CR being a Class 1 recommendation in all international guidelines, only one third of CHD patients reported being advised to attend any form of CR and just one in five patients attended 50% of the sessions, with striking heterogeneity between regions and countries. National cardiology societies should advocate to their governments for urgent investment in standardised CR services.

DOI: https://doi.org/10.5334/gh.1458 | Journal eISSN: 2211-8179
Language: English
Submitted on: May 10, 2025
Accepted on: Aug 4, 2025
Published on: Sep 2, 2025
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2025 Kornelia Kotseva, Dirk De Bacquer, Catriona Jennings, John William McEvoy, Lars Ryden, Kausik K. Ray, Gregory Y. H. Lip, Iris Erlund, Sandra Ganly, Terhi Vihervaara, Agnieszka Adamska, Ana Abreu, Wael Almahmeed, Ade Meidian Ambari, Susan Connolly, Junbo Ge, Irene Gibson, Hosam Hasan-Ali, Sue Hennessy, Yong Huo, Piotr Jankowski, Rodney M. Jimenez, Jennifer Jones, Yong Li, Ahmad Syadi Mahmood Zuhdi, Abel Makubi, Amam Chinyere Mbakwem, Lilian Mbau, Jose Luis Navarro Estrada, Okechukwu Samuel Ogah, Elijah Nyainda Ogola, Adalberto Quintero–Baiz, Mahmoud Umar Sani, Maria Ines Sosa Liprandi, Jack Wei Chieh Tan, David R Thompson, Miguel Alberto Urina Triana, Tee Joo Yeo, David Wood, Guy G. De Backer, on behalf of the INTERASPIRE Investigators, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.