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Pragmatic RE-AIM Evaluation of the Train-the-Trainer Vaccine Champions Program in Vietnam Cover

Pragmatic RE-AIM Evaluation of the Train-the-Trainer Vaccine Champions Program in Vietnam

Open Access
|May 2026

Figures & Tables

Figure 1

Theory of change.

Figure 2

Training levels and data collection points.

NIHE: National Institute of Hygiene and Epidemiology.

Table 1

Baseline characteristics of provincial trainers and vaccine champions.

CHARACTERISTICSPROVINCIAL TRAINERS
(N = 56) N (%)
VACCINE CHAMPIONS
(N = 209) N (%)
EDUCATION LEVELN = 55N = 205
High school or below1 (2)141 (69)
College, university or vocational education and training43 (78)56 (27)
Postgraduate (Masters or Doctor of Philosophy)11 (20)0 (0)
Other0 (0)8 (4)
PROFESSIONAL ROLEN = 56N = 202
Healtha37 (66)139 (69)
Communication14 (25)N/A
Otherb5 (9)63 (31)
GENDERN = 55N = 202
Male29 (53)108 (54)
Female26 (47)93 (46)
Other or prefer not to say0 (0)1 (1)
LANGUAGEN = 55N = 199
Vietnamese54 (98)169 (85)
Otherc1 (2)30 (15)
REGIONN = 56N = 204
Northwest2 (4)71 (35)
Northeast1 (2)0 (0)
Red River Delta0 (0)0 (0)
North Central Coast1 (2)0 (0)
South Central Coast4 (7)0 (0)
Central Highlands8 (14)90 (44)
Southeast7 (13)4 (2)
Mekong River Delta33 (59)39 (19)
NUMBER OF COVID‑19 VACCINE DOSES RECEIVEDN = 56N = 206
00 (0)2 (1)
11 (2)0 (0)
21 (2)2 (1)
36 (11)35 (17)
More than 348 (86)167 (81)
INTENTION TO RECEIVE ANOTHER COVID‑19 VACCINE DOSE, IF RECOMMENDEDN = 56N = 204
Yes47 (84)195 (96)
No4 (7)6 (3)
Not sure5 (9)3 (1)

[i] aFor provincial trainers, health workers included professions such as doctors, nurses, pharmacists and village health workers. For vaccine champions, health workers included professions such as village health workers, health workers and vaccination programme staff. bFor vaccine champions, ‘other’ included teachers, youth workers, police, community‑based organisations (e.g. non‑government organisations), government officials, Public Health students, tradespersons and faith leaders. N/A – not applicable. We asked the vaccine champions if they had a background in health or not; we did not give them a response option for ‘communication’. cFor vaccine champions, other languages spoken include Hmong or Mong, Khmer, Khmu (K’mu), Other, Xo Dang.

Table 2

Changes in effectiveness outcomes for provincial trainers and vaccine champions.

MEASURELEVEL 1
PROVINCIAL TRAINERS (N = 56)
LEVEL 2
VACCINE CHAMPIONS (N = 209)
VACCINE KNOWLEDGENPRE‑N
(%)
POST‑N
(%)
DIFF
(95% CI)
P‑VALUENPRE‑N (%)POST‑N
(%)
DIFF
(95% CI)
P‑VALUE
Correct identification of true statements about vaccines4341 (95)41 (95)0.0 (−11.4 to 11.4)1.000138109 (79)120 (87)8.0 (−0.5 to 16.5)0.071
Correct identification of vaccine communication techniques4127 (66)27 (66)0.0 (−17.6 to 17.6)1.00011831 (26)37 (31)5.1 (−4.2 to 14.4)0.327
Correct identification of vaccines NOT on the routine childhood schedule4444 (100)44 (100)0.0 (−2.3 to 2.3)1.000188177 (94)178 (95)0.5 (−4.0 to 5.1)1.000
Overall knowledge (all three correct)3925 (64)27 (70)5.1 (−13.2 to 23.5)0.7549024 (27)32 (36)8.9 (−1.8 to 19.6)0.115
COMMUNICATION SELF‑EFFICACY
(VERY CONFIDENT IN YOUR ABILITY TO…)
NPRE‑N
(%)
POST‑N
(%)
DIFF
(95% CI)
P‑VALUENPRE‑N (%)POST‑N
(%)
DIFF
(95% CI)
P‑VALUE
Talk about the side effects of vaccines443 (7)15 (34)27.3 (10.4 to 44.1)0.00219538 (20)68 (35)15.4 (7.4 to 23.4)<0.001
Talk about the benefits of vaccines465 (11)18 (39)28.3 (11.7 to 44.8)0.00119344 (23)77 (40)17.1 (9.3 to 24.9)<0.001
Help someone find information about vaccines441 (2)13 (30)27.3 (10.4 to 44.1)0.00219337 (19)69 (36)16.6 (8.7 to 24.5)<0.001
Start a conversation about vaccines with a hesitant person461 (2)12 (26)23.9 (8.0 to 39.8)0.00319031 (16)63 (33)16.8 (9.3 to 24.4)<0.001
TRUST AND CONFIDENCENPRE‑N
(%)
POST‑N
(%)
DIFF
(95% CI)
P‑VALUENPRE‑N (%)POST‑N
(%)
DIFF
(95% CI)
P‑VALUE
Trust the health system that provides vaccines very much4528 (62)39 (87)24.4 (6.9 to 41.9)0.007188130 (69)150 (80)10.6 (3.0 to 18.2)0.006
Think getting a COVID‑19 vaccine is very important for your health4530 (67)41 (91)24.4 (8.2 to 40.7)0.003188146 (78)161 (86)8.0 (0.7 to 15.3)0.032

[i] Pre = pre‑training result. Post = post‑training result. Diff = difference in proportions (%). CI = confidence interval. For each question, missing has been treated as missing, therefore, the sample size will vary for each question. For example, 46 provincial trainers completed both pre‑ and post‑surveys. If n = 43, three people did not answer that question in at least one of the surveys. For overall knowledge, the sample size is smaller because anyone who has not answered all three questions has been excluded.

Figure 3

Percentage difference in effectiveness outcomes (post‑training compared to pre‑training) for vaccine champions with a health and non‑health background.

BCGBacille Calmette‑Guérin
COVID‑19Coronavirus Disease 2019
EPIExpanded Program on Immunisation
HRECHuman Research Ethics Committee
N/ANot Applicable
NIHENational Institute of Hygiene and Epidemiology
RE‑AIMReach, Effectiveness, Adoption, Implementation, and Maintenance
SDG3Sustainable Development Goal Three
STROBEStrengthening the Reporting of Observational Studies in Epidemiology
UNICEFUnited Nations Children’s Fund
DOI: https://doi.org/10.5334/aogh.5116 | Journal eISSN: 2214-9996
Language: English
Page range: 47 - 47
Submitted on: Dec 1, 2025
Accepted on: May 2, 2026
Published on: May 25, 2026
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2026 Isabella Overmars, Jessica Kaufman, Thu-Anh Nguyen, Luong Tran, Thi Mai Nguyen, Ngoc Anh Vu Nguyen, Chu Huu Trang, Suzanna Vidmar, Maharajan Muthu, Gregory Fox, Shiva Shrestha, Holly Seale, Margie Danchin, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.