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Mortality of Three Major Gynecological Cancers in the European Region: An Age–Period–Cohort Analysis from 1992 to 2021 and Predictions in a 25-Year Period Cover

Mortality of Three Major Gynecological Cancers in the European Region: An Age–Period–Cohort Analysis from 1992 to 2021 and Predictions in a 25-Year Period

By: Yanxue Lian and  Pincheng Luo  
Open Access
|Jun 2025

Figures & Tables

Table 1

The trends in the three gynecological cancer mortality in the European region from 1992 to 2021.

DEATH NUMBERS (N)ALL‑AGE MORTALITYAGE‑STANDARDIZED MORTALITY (PER 1,00,000)
Number in 1992Number in 2021Percent change of numbers, 1992–2021, %Rate in 1992, per 1,00,000Rate in 2021, per 1,00,000Percent change of rate, 1992–2021, %Rate in 1992Rate in 2021Percent change of rate, 1992–2021, %Net drift of mortality, % per year
Uterine cancer23,144 (21,964 to 23,951)32,031 (28,735 to 34,200)38.45.18 (4.92 to 5.36)6.68 (5.99 to 7.14)293.5 (3.33 to 3.61)3.31 (3.02 to 3.52)–5.4–0.50 (–0.62 to −0.37)
Cervical cancer37,986 (36,605 to 39,058)30,653 (28,434 to 32,373)–19.38.51 (8.2 to 8.75)6.39 (5.93 to 6.75)–24.96.31 (6.1 to 6.47)3.82 (3.59 to 4.04)–39.5–1.78 (–1.89 to −1.67)
Ovarian cancer46,292 (44,089 to 48,038)53,324 (48,537 to 56,723)15.210.37 (9.88 to 10.76)11.12 (10.13 to 11.83)7.27.33 (7.01 to 7.6)5.87 (5.41 to 6.21)–19.9–0.97 (–1.05 to −0.89)
Figure 1

Maps of percent change in age‑standardized mortality rates for three gynecological cancers in the European region, 1992–2021.

Figure 2

Temporal change in the mortality of three gynecological cancers across age groups in the European region, 1992–2021. (A) The relative percentage of deaths by age groups for three gynecological cancers; (B) the temporal changes in the mortality rate of three gynecological cancers by age groups.

Figure 3

The local drifts, age effects, period effects, and cohort effects of three gynecological cancers‑related mortality in the European region from 1992 to 2021.

Figure 4

Observed and predicted death numbers and age‑standardized mortality rates related to three gynecological cancers in European region from 1992 to 2046.

DOI: https://doi.org/10.5334/aogh.4688 | Journal eISSN: 2214-9996
Language: English
Submitted on: Jan 21, 2025
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Accepted on: May 17, 2025
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Published on: Jun 10, 2025
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2025 Yanxue Lian, Pincheng Luo, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.