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Adult Lead Poisoning Caused by Contaminated Opium: A Two-Year Longitudinal Follow-Up Study Cover

Adult Lead Poisoning Caused by Contaminated Opium: A Two-Year Longitudinal Follow-Up Study

Open Access
|Sep 2021

Figures & Tables

Table 1

Comparison of lab values in different groups.

TEST LEVELGROUPBASELINE MEDIAN (IQR)FOLLOW-UP MEDIAN (IQR)MEAN DIFFERENCEWILCOXON p-VALUE
BLL (µg/dL)1128 (-a)17.6 (-a)–90.83  0.109
2110 (83–127.9)39.01 (28.22–46.45)–60.83  0.002
3128 (105.35–173.5)29.8 (26.57–36.92)–104.83  0.000
KW* p-value0.1890.133  0.129
Hb (g/dL)18.5 (-a)16.9 (-a)  7.5  0.109
210.27 (9.22–11.42)15.65 (15.25–16.15)  4.76  0.001
39.67 (8.05–11.12)14.9 (13.7–15.77)  5.22  0.000
KW p-value0.2760.144  0.113
Cr (mg/dL)11 (-a)1.13 (-a)  0.01  1
21.06 (0.87–1.2)1 (0.87–1.01)–0.19  0.028
31 (1.07–0.9)1.05 (0.9–1.2)  0.03  0.254
KW p-value0.5080.341  0.299
BUN (mg/dL)130 (-a)43 (-a)–6.97  1
229.73 (22.25–31.25)28.5 (23.47–36.5)  1.49  0.683
321.5 (15.75–33)35.5 (24–40.25)  8  0.071
KW p-value0.3420.515  0.780
Hct (%)126.6 (-a)45.5 (-a)  19.23  0.109
232.6 (25.7–37.4)44.9 (41.92–47.45)  11.77  0.003
328.4 (24.6–35.05)44.1 (41.5–45.77)  13.79  0.000
KW p-value0.2830.6  0.159
AST (U/L)1112 (-a)18 (-a)–69.66  0.109
253 (35–58.7)21.8 (18–27.5)–24.86  0.004
346.5 (32–83.25)25.5 (17.7–37.25)–33.72  0.001
KW p-value0.4730.705  0.461

[i] a Interquartile range (IQR) is not calculated for Group 1. KW = Kruskal Wallis.

agh-87-1-3420-g1.png
Figure 1

Baseline and follow-up BLL values in three distinct groups.

agh-87-1-3420-g2.png
Figure 2

Baseline and follow-up hemoglobin values in three distinct groups.

Table 2

Blood lead level in administered chelating agents during hospitalization and follow-up.

TREATMENTEDTA (n = 3)D-PENICILLAMINE (n = 19)BAL+EDTA (n = 9)EDTA+D-PENICILLAMINE (n = 4)KW TEST
*On-arrival BLL
(µg/dL)
69.4 [50, –]
(50, 125)
116.9 [86.7, 147]
(37, 200)
108 [83.7, 175]
(67, 200)
147.5 [101.2, 226]
(90, 248)
0.277
*Follow-up BLL
(µg/dL)
29.5 [6.1, –]
(6.1, 39.4)
32.2 [26.9, 41.5]
(7.1, 58.2)
29.1 [20.6, 33.9]
(17.16, 53.4)
42.2 [31.8, 53.6]
(29.1, 56.7)
0.272
*BLL difference
(µg/dL)
63.3 [20.5, –]
(6.1, 39.4)
78.5 [60.5, 115.1]
(-15.9, 168.9)
77.5 [46, 105.8]
(40.9, 176.8)
112.9 [60.7, 173.4]
(45.7, 191.3)
0.480

[i] * Median [IQR] (min, max); KW = Kruskal Wallis.

DOI: https://doi.org/10.5334/aogh.3420 | Journal eISSN: 2214-9996
Language: English
Published on: Sep 9, 2021
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2021 Malihe-Sadat Hosseini, Amir Salimi, Scott Phillips, Nasim Zamani, Hossein Hassanian-Moghaddam, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.