Table 1
Demographic variables of infants with vaccine complications.
| Variable | Vaccine | ||
|---|---|---|---|
| DPT | Pentavalent | ||
| Sex | Male | 5584 (53.36) | 9137 (52.1) |
| Female | 4880 (46.64) | 8399 (47.9) | |
| Location | Urban | 4025 (38.47) | 8788 (50.04) |
| Rural | 64399 (61.53) | 8773 (49.96) | |
Table 2
The frequency of adverse events DPT vaccine and Pentavalent vaccine in different provinces of Iran.
| ID | Province | Frequency of vaccination complications (%) | Total | |
|---|---|---|---|---|
| DPT | Pentavalent | |||
| 1 | Mazandaran | 1807 (17.27) | 2605 (14.83) | 4412 (15.74) |
| 2 | Qazvin | 1211 (11.57) | 1941 (11.05) | 3152 (11.25) |
| 3 | Golestan | 1409 (13.47) | 1146 (6.53) | 2555 (9.12) |
| 4 | Zanjan | 958 (9.16) | 1407 (8.01) | 2365 (8.44) |
| 5 | Khuzestan | 1019 (9.74) | 1183 (6.74) | 2202 (7.86) |
| 6 | Gilan | 84 (8.04) | 838 (4.77) | 1676 (5.99) |
| 7 | Fars | 469 (4.48) | 994 (5.66) | 1463 (5.22) |
| 8 | Isfahan | 580 (5.54) | 877 (4.99) | 1457 (5.2) |
| 9 | Alborz | 144 (1.38) | 1202 (6.84) | 1346 (4.8) |
| 10 | East Azerbaijan | 290 (2.77) | 819 (4.66) | 1109 (3.96) |
| 11 | Khorasan Razavi | 331 (3.16) | 756 (4.3) | 1087 (3.88) |
| 12 | Tehran | 255 (2.44) | 682 (3.88) | 937 (3.34) |
| 13 | Sistan & Baluchestan | 162 (1.55) | 423 (2.41) | 585 (2.09) |
| 14 | Lorestan | 99 (0.95) | 401 (2.28) | 500 (1.78) |
| 15 | West Azerbaijan | 162 (1.55) | 250 (1.42) | 412 (1.47) |
| 16 | Ardebil | 17 (0.16) | 379 (2.16) | 396 (1.41) |
| 17 | Ilam | 161 (1.54) | 221 (1.26) | 382 (1.36) |
| 18 | Yazd | 102 (0.97) | 193 (1.1) | 295 (1.05) |
| 19 | Hamedan | 93 (0.89) | 179 (1.02) | 272 (0.97) |
| 20 | Kermanshah | 48 (0.46) | 157 (0.89) | 205 (0.73) |
| 21 | North Khorasan | 39 (0.37) | 143 (0.81) | 182 (0.65) |
| 22 | Semnan | 46 (0.44) | 136 (0.77) | 182 (0.65) |
| 23 | Kerman | 53 (0.51) | 126 (0.72) | 179 (0.64) |
| 24 | Markazi | 44 (0.42) | 121 (0.69) | 165 (0.59) |
| 25 | Qom | 41 (0.39) | 83 (0.47) | 124 (0.44) |
| 26 | Kohgiluyeh & Boyer-Ahmad | 13 (0.12) | 95 (0.54) | 108 (0.39) |
| 27 | Bushehr | 17 (0.16) | 47 (0.27) | 64 (0.23) |
| 28 | Southern Khorasan | 12 (0.11) | 53 (0.3) | 64 (0.23) |
| 29 | Kurdistan | 17 (0.16) | 47 (0.27) | 64 (0.23) |
| 30 | Hormozgan | 21 (0.2) | 38 (0.22) | 59 (0.21) |
| 31 | Chaharmahal & Bakhtiari | 13 (0.12) | 95 (0.54) | 108 (0.39) |
| 32 | Total country | 10464 (100) | 1756 (100) | 28025 (100) |
Figure 1
Prevalence of Adverse Events Following Immunization with DPT Vaccine.
Figure 2
Prevalence of Adverse Events Following Immunization with Pentavalent Vaccine.
Figure 3
Comparison of Reported Adverse Events in DPT and Pentavalent Vaccines.
Table 3
The relationship between DPT and Pentavalent vaccine characteristics and their adverse events.
| Variable | Type Vaccine | Chi-2 | P-value | ||
|---|---|---|---|---|---|
| DPT | Pentavalent | ||||
| Type of reaction | Severe localized condition | 1375 (7.83) | 1377 (13.16) | 3.8 | 0.0001 |
| High fever* | 4944 (28.15) | 4960 (47.4) | |||
| Fever | 1997 (11.37) | 120 (1.15) | |||
| Mild localized condition | 5564 (31.68) | 2018 (19.29) | |||
| Lyme abscess | 576 (3.28) | 170 (1.62) | |||
| Seizures caused by fever | 287 (1.63) | 186 (1.78) | |||
| Screaming constantly | 614 (3.5) | 605 (5.78) | |||
| Loss of consciousness | 91 (0.52) | 45 (0.43) | |||
| Paralysis of the limb | 3 (0.02) | 2 (0.02) | |||
| Diarrhea and vomiting | 277 (1.58) | 858 (8.2) | |||
| Others | 1833 (10.44) | 123 (1.18) | |||
| Complaint classification | Programming error | 718 (4.4) | 298 (2.85) | 263.1 | 0.0001 |
| Reactions to vaccines | 15099 (92.47) | 10110 (96.63) | |||
| Reaction to the injection | 287 (1.76) | 489(0.46) | |||
| Concurrency | 139 (0.85) | 4 (0.04) | |||
| Unknown | 85 (0.52) | 3 (0.03) | |||
| Hospitalization | Yes | 157 (1.5) | 420 (2.39) | 0.11 | 0.7 |
| No | 10307 (98.5) | 17141 (61.97) | |||
| Report type | Immediate | 472 (4.51) | 966 (5.5) | 13.19 | 0.0001 |
| Non-Immediate | 9992 (95.49) | 16595 (94.5) | |||
| Gender | Male | 5584 (53.36) | 9137 (52.1) | 4.2 | 0.05 |
| Female | 4880 (46.64) | 8399 (52.1) | |||
| Location | Urban | 4025 (38.47) | 8788 (47.9) | 354 | 0.0001 |
| Rural | 6439 (61.53) | 8773 (49.96) | |||
[i] * High fever is defined as higher than 39c.