Fig. 1
A schematic representation of the phototransduction cascade separated into modules and showing the positive (red) and negative (blue lines) feedbacks.
Fig. 2
GUI designed for running the simulation software. Contains all main parameters and details about the simulation execution.
Fig. 3
Output Results for the example of the Input parameters shown in Fig. 2. (A) The average quantum bump for aligned QBs for: experimental 79 QBs (data obtained from R. C. Hardie, University of Cambridge, shown by red circles) and the model fit for a set of 178 QBs (line), produced for 200 light flashes. QB events were filtered (100 Hz), aligned and averaged (see text). (B) Latency distribution for the onset of QB events (total of 178 QBs). (C) the peak current distribution. Note: 200 runs might take about one hour on a HP ZX800 workstation. Since each run produces a stochastic event although average values are shown here in any specific repeat of this programme slightly different results might be expected.