Outcome of partial cystectomy for non-urothelial urinary bladder malignancies in a tertiary care urology unit in Sri Lanka

Introduction
Non-urothelial bladder cancers (NUBC) are very aggressive form of tumors and the standard treatment is radical cystectomy which is associated with high morbidity. This study was aimed to describe the outcome of partial cystectomy for selected patients with NUBC in a tertiary care urology unit in Sri Lanka.

Methods
A retrospective analysis of all patients (n=7, males=4) who underwent partial cystectomy for NUBC in a tertiary care urology unit in National Hospital of Sri Lanka over a period of 16 years was done (From 2001 to 2016). All underwent preliminary transurethral resection of bladder tumour (TURBT), histological confirmation and imaging before partial cystectomy. Lymphadenectomy was performed in patients with macroscopic involvement.

Results
The median age was 59 years (range:40-71). Six patients had haematuria at presentation. Four patients had primary adenocarcinoma of the bladder. Others were leiomyosarcoma, small cell cancer and goblet cell carcinoid tumour. The majority had muscle invasive disease as confirmed by histopathology. The patients with signet ring cell carcinoma, leiomyosarcoma and well differentiated adenocarcinoma had favorable outcomes, while patients with papillary carcinoma, small cell carcinoma and goblet cell carcinoid tumour showed poor outcomes.

Conclusion
Partial cystectomy was associated with variable outcomes. Further analyses are necessary to understand the factors associated with favorable outcomes which would be helpful in patient selection.