Childhood Eosinophilic meningitis: two case reports

Introduction: Eosinophilic meningitis (EM) is a rare form of meningitis caused by parasitic infestations, Hypereosinophilic syndrome and neoplasms.

 

Case Presentation: We present two EM cases with no clear evidence of parasitic infestation or malignancy, who responded well to steroid treatment. Both of the patients presented with high-grade fever and features of central nervous system involvement. Both patients had moderate to severe Eosinophilia in blood and cerebrospinal fluid. The patients were treated with broad-spectrum intravenous antibiotics and anti-helminthic drugs with no improvement. However, there was a marked clinical improvement after commencing steroids.

 

Discussion: Even though the diagnosis of EM was made easily, we could not find an exact aetiology. However, both patients showed a remarkable improvement with our management and no deterioration was observed during the follow-up.