Post-streptococcal glomerulonephritis complicated with reversible posterior leukoencephalopathy syndrome

Introduction: Reversible posterior leukoencephalopathy syndrome (RPLS) is a clinical condition with headache, altered behavior, visual symptoms and seizures. It is associated with characteristic neuroimaging which shows vasogenic edema at occipital and parietal region commonly. Post-streptococcal glomerulonephritis (PSGN) is uncommonly associated with RPLS. 

 

Case Presentation: We report a case of 15 years old boy who presented with recurrent seizure and progressive visual impairment ten days following a sore throat, subsequently diagnosed to have PSGN with MRI evidence of RPLS. He was commenced on oral phenoxymethylpenicillin and oral verapamil. Repeat MRI after six weeks showed complete resolution of previous changes. This is a rare case of RPLS associated with PSGN.