Megarbane-Loiselet neonatal progeroid syndrome; a rare cause for neonatal progeroid syndrome

Premature ageing syndromes are a rare group of disorders. True premature ageing, skin atrophy/ lipoatrophy, cutis laxa or simply an older appearance than would be expected for the person's age lead to this phenotype. Many of these conditions share common clinical manifestations which can make difficulty in precise diagnosis. Conditions with lipoatrophy are also described as neonatal progeroid syndromes. In this case report we describe a 2 month old child with manifestations of Megarbane-Loiselet neonatal progeroid (MLNP) syndrome, a neonatal progeroid syndrome for its rareness.