A case of Kimura's disease

Kimura's disease is not uncommon in Asia even though it is a rare entity in the West. It clinically manifests as solitary or multiple subcutaneous nodules in the head and neck region. It can be accompanied by regional lymphadenopathy and salivary gland hypotrophy.

Histology is characterized by vascular proliferation, hyperplastic lymphoid tissue and inflammatory infiltrate rich in Eosinophills eosinophillla can sometimes be seen. It can be associated with nephrotic syndrome. Prognosis is good and there is no malignant transformation.

We report a 24-year old male who presented with asymptomatic solitary subcutaneous nodule in L/S nasal bridge for 2 years duration. It has gradually enlarged in size. There were no regional adenopathy or salivary gland hypertrophy. Histology was suggestive of Kimura's disease, and fungal studies were negative. There was no eosinophilia or evidence of nephrotic syndrome.

We treated him with intralesional steroid for which he responded. A man with Kimura's disease has been reported previously in Sri Lanka. To our knowledge, this is the second case reported from Sri Lanka. We report this case to emphasize that Kimura's disease should be considered as a differential diagnosis for subcutaneous nodules in the head and neck region.