What's HITECH About CRS-HIPEC?

Hyperthermic intraperitoneal chemotherapy (HIPEC) is a technique, which delivers heated chemotherapeutic agents into the peritoneal cavity. It has been shown to improve prognosis and survival rate in patients of colorectal, ovarian and gastric cancers with peritoneal metastasis. A 57-year-old man diagnosed with primary colorectal carcinoma and pseudomyxoma peritonei was posted for HIPEC surgery. General anaesthesia with epidural analgesia (pain management) and invasive lines (arterial, central) for managing fluid shifts were used. Stroke volume variation was measured throughout the 19-hour procedure for goal directed fluid therapy (GDT) and to maintain urine output. Temperature monitoring with deliberate cooling measures were used during the period of HIPEC along with serial arterial blood gas analysis (ABG).