A patient with Beta thalassaemia major presenting with cauda equine syndrome due to extramedullary haematopoiesis

Beta-thalassaemia major is a hereditary haematological disorder characterized by anomalies in the synthesis of the beta chains of hemoglobin resulting in anaemia requiring repeated blood transfusions. Inadequately transfused patients commonly present with growth retardation, hepatosplenomegaly, leg ulcers and skeletal changes resulting from expansion of the bone marrow. Cauda equina syndrome or spinal cord compression by extramedullary haematopoiesis has also rarely been reported due to development of masses. We report a case of 16 year old female with beta-thalassaemia major who presented with bilateral lower limb paralysis secondary to cauda equina syndrome with extra medullary haematopoiesis.