Clinical Profile and Outcome of Symptomatic COVID 19 Infection among Vaccinated Patients Admitted to Teaching Hospital Jaffna

COVID-19 (Corona Virus Disease) was a pandemic disease affecting the world leading to a large number of morbidity and mortality all over the world. The introduction of vaccines for this disease has been the cornerstone to fight this disease. In this study, we analyzed the clinical profile and outcome of symptomatic COVID-19 infection among vaccinated patients admitted to Teaching Hospital Jaffna.
We conducted a population-based descriptive type of observational study on symptomatic COVID-19 patients admitted to teaching hospital Jaffna who had taken at least one dose of the COVID-19 vaccine. A total number of 349 Symptomatic COVID-19 patients admitted to teaching hospital Jaffna who had taken at least one dose of COVID-19 vaccine were recruited to the study from December 2021 to March 2022. An interviewer-administered questionnaire was used to get the general information of the participants including age, gender, area of residence, and prevailing medical conditions. To decide the severity of infection and complications a data sheet was used. This was filled by checking the bedhead ticket. Data were entered into an Excel data sheet and descriptive statistics and chi-square tests were analyzed using Statistical Package for Social Sciences (SPSS) version 21.
According to the study the patients who had taken both doses had less severe illness (79.8%) compared to those who had taken a single dose (33.3%) and there was a reduction in severity with the duration of vaccination. There was no association between severity of the disease and gender but there was an increase in severity of illness and death with increasing age. Our study also demonstrates that, with an increased number of comorbidities there is an increase in the severity of infection
In our study, all the vaccines were effective in reducing the severity of the illness. However, there are a number of patients who had severe illness despite taking the full vaccination. There are factors such as advancing age and the number of comorbidities also influence the severity of illness. There was no association between the severity of the disease and gender.