Changing trend of oesophageal adenocarcinoma and cardia carcinoma incidence; review of literature and analysis

Objective:

To assess the incidence trends of oesophageal adenocarcinoma and cardia carcinoma in Asian countries based on published literature.

Method:

Medical literature was searched by using MEDLINE (1991 to 2011). Latest incidence data were obtained from the web site of the International Agency for Research on Cancer.

Results:

In the Asian countries squamous cell carcinoma (SCC) remains the most common oesophageal carcinoma. In the East Asian region, although the incidence of oesophgeal adenoacarcinoma (OAC) is relatively high, each country appears to have different incidence trends of OAC. In most of these countries relative incidence trends of cardia carcinoma (CC) appear to follow those of OAC, regardless of the direction of the trend. CC and gastric non cardia carcinoma (GNCC) have opposing trends.

Conclusion:

These observations support the hypothesis that aetiopathogenesis of CC and GNCC are different. In South Asian countries, published data are not adequate to comment on the incidence trends of OAC and CC.

DOI: http://dx.doi.org/10.4038/jdp.v6i1.4418

Journal of Diagnostic Pathology 2011(6); 1: 17-27