Primary mucinous adenocarcinoma of renal pelvis: a case report

Primary mucinous adenocarcinoma of the renal pelvis is a very rare tumour which is usually associated with urolithiasis and hydronephrotic changes due to chronic irritation and infection, leading to glandular metaplasia of lining urothelial cells. We present a 62- year old male with a history of ureteric calculi 7 years back now presenting with pain in the left flank and a palpable mass at left loin who was diagnosed clinically and radiologically to have hydronephrosis with a non functioning kidney. He underwent radical nephrectomy. On histopathological examination he was diagnosed to have mucinous adenocarcinoma of the renal pelvis stage PT4N1M0. Immunohistochemically the tumour cells were positive for CK7 and negative for CK20 and focally positive for CDX2.