Early clinical experience with the new Amplatzer Ductal Occluder II for closure of the Persistent Arterial Duct (PDA)

Introduction: Transcatheter PDAclosure has gained acceptance over surgery because of its cosmetic benefits, shorter hospital stay and absence of pain associated with a thoracotomy. The Amplatzer Ductal Occluder II (ADOII) device provides a solution for the closure of small to moderate-sizedPDAs

Objective: To describe early single-centre clinical experience withADOII.

Methods: Children with a haemodynamically significant patent ductus arteriosus (PDA) who underwent percutaneous trans-pulmonary closure with Amplatzer Ductal Occluder II (ADO II) were included. Data was collected from computer based patient records.

Results: Trans-pulmonary PDAclosures usingADOII were undertaken in 65 children (46 females) with a mean age of 2years 3 months (range 5 months to 14 years) and a mean weight of 9.6kg (range 4.2-25kg).

Complete occlusion was noted pre-discharge in 64 (98.4%) patients. One (1.6%) had residual shunting after deployment followed by embolization to the left pulmonary artery on the third day of the procedure. Of the 65 children, five (7.7%) had mild flow acceleration in the left pulmonary artery and another one (1.6%) had mild aortic flow obstruction following the procedure.

 At 7 and 30 days, echocardiography confirmed complete ductal occlusion without need for further intervention in all 64 (98.4%) successful cases.

 Conclusions: ADO II is highly effective in rapid occlusion of morphologically varied small to moderate-sized PDAs.