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The Impact of Undetected Hyperglycaemia During Pregnancy on Maternal and Neonatal Outcomes Cover

The Impact of Undetected Hyperglycaemia During Pregnancy on Maternal and Neonatal Outcomes

Open Access
|Oct 2024

Figures & Tables

Figure 1.

The results of the 75 g oral glucose tolerance test in the group of pregnant patients with undetected hyperglycaemia (1st group).
The results of the 75 g oral glucose tolerance test in the group of pregnant patients with undetected hyperglycaemia (1st group).

Diagnostic criteria for GDM in OGTT included in selected recommendations_

WHO 1999GDMCriteria for DMFasting ≥ 126 mg/dl (7.0 mmol/l)
or
2-h post glucose ≥ 200 mg/dl (11.1 mmol/l)
Criteria for IGTFasting < 126 mg/dl (7.0 mmol/l)
and
2-h post glucose ≥ 140 mg/dl (7.8 mmol/l)
PGS 2011GDMOne of the following:Fasting ≥ 100 mg/dl (5.6 mmol/l)
1-h ≥180 mg/dl (10.0 mmol/l)
2-h ≥ 140 mg/dl (7.8 mmol/l)
WHO 2013 PGS 2015GDMOne of the following:Fasting 92 – 125 mg/dl (5.1 mmol/l)
1-h ≥ 180 mg/dl (10.0 mmol/l)
2-h ≥ 153 mg/dl (8.5 mmol/l)

The comparison of course of pregnancy, neonatal and maternal outcomes in both groups – 1st group with undetected hyperglycaemia, 2nd group with GDM during pregnancy and adequate therapeutic management_

1st group (n=40)2nd group (n=40)P value
Characteristics of pregnant patients:
Age in years – mean (SD) 32.8 (5.14)32.0 (5.31)0.536
BMI (kg/m^2) – mean (SD) 31.8 (5.30)31.4 (5.50)0.743
Primigravida – n (%) 14 (35)23 (57.5)0.044
Multigravida – n (%) 26 (65)17 (42.5)
Maternal outcomes:
Hypertensive disorders during pregnancy - hypertension, preeclampsia, HELLP (%)7 (17.5)7 (17.5)1.00
Time of delivery – weeks of gestation39+239+10.787
The route of delivery:Elective caesarean section5120.121
Emergency caesarean section1214
Vaginal delivery2214
Instrumental delivery (forceps)10
Neonatal outcomes:
Neonatal weightSGA – n (%)4 (10)5 (12.5)0.039
AGA – n (%)30 (75)35 (87.5)
LGA – n (%)6 (15)0 (0)
Hyperbilirubinaemia – n (%) 9 (22.5)1 (2.5)0.007
Hypoglycaemia <40 mg/dl – n (%)3 (7.5)5 (12.5)0.456

The compliance with recommended diagnostics in postpartum period in patients from both groups_

1st group (n=28)2nd group (n=28)P value
Did not perform the OGTT (%)21 (75)10 (36)0.003
Performed the OGTT (%)7 (25)18 (64)
DOI: https://doi.org/10.34763/jmotherandchild.20242801.d-24-00004 | Journal eISSN: 2719-535X | Journal ISSN: 2719-6488
Language: English
Page range: 87 - 93
Submitted on: Jan 28, 2024
|
Accepted on: Jun 26, 2024
|
Published on: Oct 23, 2024
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2024 Olga Olszak, Jarosław Kalinka, published by Institute of Mother and Child
This work is licensed under the Creative Commons Attribution 4.0 License.