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A Current Management Strategy for Children with Chronic Viral Hepatitis B, Based on International and National Guidelines Cover

A Current Management Strategy for Children with Chronic Viral Hepatitis B, Based on International and National Guidelines

Open Access
|Aug 2023

References

  1. Global progress report on HIV, viral hepatitis and sexually transmitted infections, 2021. Accountability for the global health sector strategies 2016–2021: actions for impact. World Health Organization. Geneva: World Health Organization, 2021; 108 p. ISBN 978-92-4-002708-4 (print version) ISBN 978-92-4-002707-7 (electronic version). Available from: https://www.who.int/publications/i/item/9789240027077
  2. Global health sector strategy on viral hepatitis 2016–2021: Towards ending viral hepatitis. World Health Organization. Geneva: World Health Organization, 2016; 53 p. WHO reference number: WHO/HIV/2016.06. Available from: https://www.who.int/publications/i/item/WHO-HIV-2016.06
  3. Progress report on HIV, viral hepatitis and sexually transmitted infections 2019: accountability for the global health sector strategies, 2016–2021. World Health Organization. Geneva : World Health Organization, 2019; 39 p. WHO Document number: WHO/CDS/HIV/19.7. Available from: https://apps.who.int/iris/handle/10665/324797
  4. Combating hepatitis B and C to reach elimination by 2030: advocacy brief. World Health Organization. Geneva: World Health Organization, 2016; 17 p. WHO document number: WHO/HIV/2016.04. Available from: https://apps.who.int/iris/handle/10665/206453
  5. Cox AL, El-Sayed MH, Kao JH, Lazarus JV, Lemoine M, Lok AS, et al. Progress towards elimination goals for viral hepatitis. Nat Rev Gastroenterol Hepatol. 2020;17(9):533–42. doi: 10.1038/s41575-020-0332-6
  6. Thomas DL. Global Elimination of Chronic Hepatitis. N Engl J Med. 2019;380(21):2041–50. doi: 10.1056/NEJMra1810477
  7. Bertoletti A, Kennedy PT. The immune tolerant phase of chronic HBV infection: new perspectives on an old concept. Cell Mol Immunol. 2015;12(3):258–63. doi: 10.1038/cmi.2014.79
  8. Khanam A, Chua JV, Kottilil S. Immunopathology of Chronic Hepatitis B Infection: Role of Innate and Adaptive Immune Response in Disease Progression. Int J Mol Sci. 2021;22(11):5497. doi: 10.3390/ijms22115497
  9. Terrault NA, Lok ASF, McMahon BJ, Chang KM, Hwang JP, Jonas MM, et al. Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance. Hepatology. 2018;67(4):1560–99. doi: 10.1002/hep.29800
  10. Revill PA, Chisari FV, Block JM, Dandri M, Gehring AJ, Guo H, et al.; Members of the ICE-HBV Working Groups; ICE-HBV Stakeholders Group Chairs; ICE-HBV Senior Advisors; Zoulim F. A global scientific strategy to cure hepatitis B. Lancet Gastroenterol Hepatol. 2019;4(7):545–558. doi: 10.1016/S2468-1253(19)30119-0. Erratum in: Lancet Gastroenterol Hepatol. 2019 Jul;4(7):e7. doi: doi: 10.1016/S2468-1253(19)30151-7
  11. Bhat SA, Kazim SN. HBV cccDNA-A culprit and stumbling block for the hepatitis B virus infection: its presence in hepatocytes perplexed the possible mission for a functional cure. ACS Omega. 2022;7(28):24066–81. doi: 10.1021/acsomega.2c02216
  12. Revill PA, Penicaud C, Brechot C, Zoulim F. Meeting the challenge of eliminating chronic hepatitis B infection. Genes (Basel). 2019;10(4):260. doi: 10.3390/genes10040260
  13. Lucifora J, Protzer U. Attacking hepatitis B virus cccDNA—the holy grail to hepatitis B cure. J Hepatol. 2016;64(1 Suppl):S41–S48. doi: 10.1016/j.jhep.2016.02.009
  14. Indolfi G, Abdel-Hady M, Bansal S, Debray D, Smets F, Czubkowski P, et al. Management of hepatitis B virus infection and prevention of hepatitis B virus reactivation in children with acquired immunodeficiencies or undergoing immune suppressive, cytotoxic, or biological modifier therapies. J Pediatr Gastroenterol Nutr. 2020;70(4):527–538. doi: 10.1097/MPG.0000000000002628
  15. Hepatitis B. pp. 401-28. In: Kimberlin DW, Brady MT, Jackson MA, Long SS, editors. Red Book: 2018–2021 Report of the Committee on Infectious Diseases. Committee on Infectious Diseases, American Academy of Pediatrics. 31st Edition. Itasca, IL: American Academy of Pediatrics, 2018:401–28. ISBN 978-1-61002-146-3. doi: 10.1542/9781610021470 (book doi). doi: 10.1542/9781610021470-part03-hepatitis_b (chapter doi)
  16. El Agheb MO, Grange JD. Prévention de la transmission mèreenfant de l’hépatite B. (Prevention of mother to child transmission of hepatitis B). Pan Afr Med J. 2015;20:316. French. doi: 10.11604/pamj.2015.20.316.6193
  17. European Association for the Study of the Liver; Collaborators: Lampertico P, Agarwal K, Berg T, Buti M, Janssen HLA, Papatheodoridis G, et al. EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection. J Hepatol. 2017 Aug;67(2):370–398. doi: 10.1016/j.jhep.2017.03.021
  18. Croagh CM, Lubel JS. Natural history of chronic hepatitis B: phases in a complex relationship. World J Gastroenterol. 2014;20(30):10395–404. doi: 10.3748/wjg.v20.i30.10395
  19. Bortolotti F, Guido M, Bartolacci S, Cadrobbi P, Crivellaro C, Noventa F, et al. Chronic hepatitis B in children after e antigen seroclearance: final report of a 29-year longitudinal study. Hepatology. 2006;43(3):556–62. doi: 10.1002/hep.21077
  20. Lu FT, Ni YH. Elimination of mother-to-infant transmission of hepatitis B virus: 35 years of experience. Pediatr Gastroenterol Hepatol Nutr. 2020;23(4):311–8. doi: 10.5223/pghn.2020.23.4.311
  21. Komatsu H, Inui A, Fujisawa T. Pediatric hepatitis B treatment. Ann Transl Med. 2017;5(3):37. doi: 10.21037/atm.2016.11.52
  22. Stinco M, Rubino C, Trapani S, Indolfi G. Treatment of hepatitis B virus infection in children and adolescents. World J Gastroenterol. 2021;27(36):6053–63. doi: 10.3748/wjg.v27.i36.6053
  23. Mysore KR, Leung DH. Hepatitis B and C. Clin Liver Dis. 2018;22(4):703–22. doi: 10.1016/j.cld.2018.06.002
  24. WHO guidelines on hepatitis B and C testing. World Health Organization. Geneva: World Health Organization, 2017; 170 p. ISBN 978-92-4-154998-1. Available from: https://www.who.int/publications/i/item/9789241549981
  25. Costa JM, Telehin D, Munteanu M, Kobryn T, Ngo Y, Thibault V, et al. HCV-GenoFibrotest: a combination of viral, liver and genomic (IL28b, ITPA, UGT1A1) biomarkers for predicting treatment response in patients with chronic hepatitis C. Clin Res Hepatol Gastroenterol. 2011;35(3):204–13. doi: 10.1016/j.clinre.2011.01.005
  26. Mărginean CO, Meliț LE, Săsăran MO. Elastography—a bona fide non-invasive method for assessing non-alcoholic fatty liver disease in children. Applied Sciences. 2021;11(7):3240. doi: 10.3390/app11073240
  27. Rodriguez-Baez N, Murray KF, Kleiner DE, Ling SC, Rosenthal P, Carlin K, et al. Hepatic histology in treatment-naïve children with chronic hepatitis B infection living in the United States and Canada. J Pediatr Gastroenterol Nutr. 2020;71(1): 99–105. doi: 10.1097/MPG.0000000000002712
  28. Indolfi G, Easterbrook P, Dusheiko G, Siberry G, Chang MH, Thorne C, et al. Hepatitis B virus infection in children and adolescents. Lancet Gastroenterol Hepatol. 2019;4(6):466–76. doi: 10.1016/S2468-1253(19)30042-1. Erratum in: Lancet Gastroenterol Hepatol. 2020;5(5):e4. doi: 10.1016/S2468-1253(20)30092-3
  29. Wong WWL, Pechivanoglou P, Wong J, Bielecki JM, Haines A, Erman A, et al. Antiviral treatment for treatment-naïve chronic hepatitis B: systematic review and network meta-analysis of randomized controlled trials. Syst Rev. 2019;8(1):207. doi: 10.1186/s13643-019-1126-1
  30. Wei S, Hu M, Chen H, Xie Q, Wang P, Li H, et al. Effectiveness of antiviral treatment in HBeAg-negative chronic hepatitis B patients with normal or mildly elevated alanine aminotransferase: a retrospective study. BMC Gastroenterol. 2022;22(1):387. doi: 10.1186/s12876-022-02471-y
  31. Li M, Sun F, Bi X, Lin Y, Yang L, Lu Y, et al. Consolidation treatment needed for sustained HBsAg-negative response induced by interferon-alpha in HBeAg positive chronic hepatitis B patients. Virol Sin. 2022;37(3):390–7. doi: 10.1016/j.virs.2022.03.001
  32. Pan J, Wang H, Yao T, Liao X, Cheng H, Liangpunsakul S, et al. Clinical predictors of functional cure in children 1–6 years-old with chronic hepatitis B. J Clin Transl Hepatol. 2022;10(3):405–11. doi: 10.14218/JCTH.2021.00142
  33. Zhong YW, Shi YM, Chu F, Liu J, Shi C, Xu JJ, et al. Prediction for HBsAg seroconversion in children with chronic hepatitis B. BMC Infect Dis. 2021;21(1):1211. doi: 10.1186/s12879-021-06883-1
  34. Sarin SK, Kumar M, Lau GK, Abbas Z, Chan HL, Chen CJ, et al. Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update. Hepatol Int. 2016;10(1):1–98. doi: 10.1007/s12072-015-9675-4.
  35. Guidelines for the prevention, care and treatment of persons with chronic hepatitis B infection. World Health Organization; Global HIV, Hepatitis and Sexually Transmitted Infections Programmes. Geneva, Switzerland : WHO, March 2015; XXX, 134 p. ISBN 978 92 4 154905 9. Available from: https://www.who.int/publications/i/item/9789241549059
  36. NICE National Institute for Health and Care Excellence. Hepatitis B (chronic): diagnosis and management : clinical guideline. CG165. London, Manchester, UK: NICE, published June 2013, corrected January 2014, last updated October 2017; 36 p. Published 26 June 2013. Las Updated 20 October 2017. ISBN 978-1-4731-4724-9. Available from: https://www.nice.org.uk/guidance/cg165
  37. Sokal EM, Paganelli M, Wirth S, Socha P, Vajro P, Lacaille F, Kelly D, Mieli-Vergani G; European Society of Pediatric Gastroenterology, Hepatology and Nutrition. Management of chronic hepatitis B in childhood: ESPGHAN clinical practice guidelines: consensus of an expert panel on behalf of the European Society of Pediatric Gastroenterology, Hepatology and Nutrition. J Hepatol. 2013 Oct;59(4):814–29. doi: 10.1016/j.jhep.2013.05.016
DOI: https://doi.org/10.34763/jmotherandchild.20232701.d-23-00006 | Journal eISSN: 2719-535X | Journal ISSN: 2719-6488
Language: English
Page range: 134 - 141
Submitted on: Jan 4, 2023
Accepted on: Jun 23, 2023
Published on: Aug 31, 2023
Published by: Institute of Mother and Child
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2023 Inna M. Nesina, Tetyana O. Kryuchko, Olha A. Poda, Olha Ya. Tkachenko, Nataliia V. Kuzmenko, Liudmyla M. Bubyr, published by Institute of Mother and Child
This work is licensed under the Creative Commons Attribution 4.0 License.