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Determinants of Childhood Asthma: A Case Control Study from a Tertiary Care Hospital in Bengaluru, South India Cover

Determinants of Childhood Asthma: A Case Control Study from a Tertiary Care Hospital in Bengaluru, South India

Open Access
|Aug 2023

Figures & Tables

j_jmotherandchild_20232701_d-22-00059_tab_005

Andrea Daniella JohnsonAlex FernandoMaria LewinFarah Naaz Fathima
Conceptualisation
Data curation--
Formal analysis--
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Investigation
Methodology
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Writing- reviewing and editing

Environment and housing factors in childhood asthma N=60_

VariableCategoryCases (30)N (%)Controls (30)N (%)Odds Ratio(95% CI)P-value
ResidenceRural12 (40.0)19 (63.3)0.87 (0.31–2.46)0.79
Urban18 (60.0)11 (36.7)
Located in industrial areaYes13 (13.3)1 (3.3)22.18 (2.66–184.79)0.001
No17 (86.7)29 (96.7)
Location of houseMain road15 (50.0)8 (26.7)2.75 (0.93–8.1)0.06
Away from main road15 (50.0)22 (73.3)
OvercrowdingYes16 (53.3)12 (40.0)1.71 (0.62–4.77)0.30
No14 (46.7)18 (60.0)
Exposure to tobacco smokeYes6 (20.0)5 (16.7)1.25 (0.34–4.64)0.74
No24 (80.0)25 (83.3)
Exposure to firewoodYes3 (10.0)6 (20.0)0.44 (0.1–1.97)0.28
No27 (90.0)24 (80.0)
Exposure to incenseYes17 (56.7)7 (23.3)4.3 (1.41–13.07)0.01
No13 (43.3)23 (76.7)
Exposure to mosquito repellantsYes15 (50.0)8 (26.7)2.75 (0.93–8.1)0.06
No15 (50.0)22 (73.3)
Kerosene for cookingYes6 (20.0)7 (23.3)0.82 (0.24–2.81)0.75
No24 (80.0)23 (76.7)
Pets in the houseYes12 (40.0)7 (23.3)2.19 (0.72–6.7)0.17
No18 (60.0)23 (76.7)
Synthetic material of child's pillow coverYes4 (13.3)8 (26.7)0.42 (0.11–1.6)0.2
No26 (86.7)22 (73.3)
Regular washing child's bedlinenYes27 (90.0)24 (80.0)2.25 (0.51–9.99)0.28
No3 (10.0)6 (20.0)
Child plays with soft toysYes15 (50.0)11 (36.7)1.73 (0.62–4.84)0.32
No15 (50.0)19 (63.3)
Cockroach infestation at homeYes22 (73.3)17 (56.7)2.1 (0.71–6.22)0.18
No8 (26.7)13 (43.3)
Heavy carpet/curtain/rugs at homeYes15 (50)6 (20)4.00 (1.27–12.58)0.02
No15 (50)24 (80)

Pre-natal, genetic and birth factors in childhood asthma N=60_

VariableCategoryCases (30)N (%)Controls (30)N (%)Odds Ratio(95% CI)P-value
Parity index of motherPrimipara9 (30.0)9 (30.0)1.0 (0.33–3.01)0.99
Multipara21 (70.0)21 (70.0)
Birth order116 (53.3)21 (70.0)0.49 (0.17–1.41)0.18
≥214 (46.7)9 (30.0)
Parental history of allergy / atopyYes14 (46.7)0 (0)3.98 (1.10–6.86)0.007*
No16 (53.3)30 (100)
Gestational age at birthPreterm5 (16.7)7 (23.3)0.66 (0.18–2.36)0.52
Full term25 (83.3)23 (76.7)
Mode of deliveryVaginal (normal/assisted)19 (63.3)23 (76.7)0.53 (0.17–1.62)0.26
Caesarean section11 (36.7)7 (23.3)
Birth weight< 2500 g4 (13.3)8 (26.7)0.42 (0.11–1.59)0.17
≥ 2500 g26 (86.7)22 (73.3)

Sociodemographic factors in childhood asthma N=60_

VariableCategoryCases (30)N (%)Controls (30)N (%)Odds Ratio(95% CI)P-value
AgeUnder 517 (56.7)16 (53.3)1.14 (0.41–3.16)0.79
Above 5yrs13 (43.3)14 (46.7)
GenderMale18 (60.0)18 (60.0)1.00 (0.36–2.81)0.99
Female12 (40.0)12 (40.0)
Maternal educationUp to High school20 (66.7)25 (83.3)0.4 (0.19–1.36)0.14
Graduate/Postgraduate10 (33.3)5 (16.7)
Socioeconomic statusUpper/upper-middle18 (60.0)13 (43.3)1.96 (0.70–5.48)0.19
Middle/Lower-middle/lower12 (40.0)17 (56.7)

Risk factors for childhood asthma in neonatal period, infancy and childhood N=60_

VariableCategoryCases (30)N (%)Controls (30)N (%)Odds Ratio(95% CI)P-value
Received pre-lacteal feedsYes13 (43.3)11 (36.7)1.32 (0.47–3.72)0.60
No17 (56.7)19 (63.3)
Exclusive breastfeeding for 6 monthsYes17 (56.7)24 (80.0)0.33 (0.1–1.03)0.052
No13 (43.3)6 (20.0)
Experienced respiratory problems in the neonatal periodYes12 (40.0)3 (10.0)6.00 (1.48–24.3)0.01
No18 (60.0)27 (90.0)
NICU admissionYes11(36.7)6 (20.0)2.32 (0.72–7.41)0.15
No19(63.3)24 (80.0)
Any illness in the first yearYes24 (80.0)12 (40.0)6.00 (1.89–19.04)0.002
No6 (20.0)18 (60.0)
Child experiences symptoms of allergic rhinitisYes23(76.7)2 (6.7)46 (8.7–243.25)<0.001
No7 (23.3)28 (93.3)
History of atopy/allergyYes6 (20.0)0 (0)2.78 (0.14–5.71)0.06*
No24 (80.0)30 (100)
Nutritional status (present)Overweight5 (16.7)9 (30.0)--
Normal22 (73.3)20 (66.7)0.33 (0.03–3.21)0.34
Underweight3 (10.0)2 (3.3)0.91 (0.49–1.67)0.76
DOI: https://doi.org/10.34763/jmotherandchild.20232701.d-22-00059 | Journal eISSN: 2719-535X | Journal ISSN: 2719-6488
Language: English
Page range: 107 - 113
Submitted on: Oct 10, 2022
Accepted on: Mar 4, 2023
Published on: Aug 31, 2023
Published by: Institute of Mother and Child
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2023 Andrea Daniella Johnson, Alex Fernando, Maria Lewin, Farah Naaz Fathima, published by Institute of Mother and Child
This work is licensed under the Creative Commons Attribution 4.0 License.