Figure 1.
Maternal and Obstetric Outcomes
| Parameters | Unvaccinated N=154 | Vaccinated N=127 | p value |
|---|---|---|---|
| Gestational age at delivery | 37.6 ± 2.4 | 37.1 ± 2.1 | 0.033 |
| Gestational age at delivery <34 weeks | 7 (4.54%) | 6 (4.72%) | 0.07 |
| Gestational age at delivery <37 weeks | 33 (21.42%) | 17 (13.28%) | 0.001 |
| Vaginal delivery | 63 (40.90%) | 48 (37.79%) | 0.041 |
| Caesarean delivery | 91 (59.09%) | 79 (62.20%) | |
| Anaemia (Hb <7gm/dl) | 8 (5.19%) | 6 (4.72%) | 0.495 |
| Gestational + pregestational Diabetes | 10 (6.49%) | 4 (3.14%) | 0.2 |
| Hypertension in pregnancy | 9 (5.84%) | 10 (7.87%) | 0.555 |
| PPROM | 8 (5.19%) | 11 (8.66%) | 0.43 |
| Hypothyroidism | 17 (11.03%) | 17 (13.38%) | 0.548 |
Fetal and Neonatal Outcomes
| Unvaccinated N=154 | Vaccinated N=127 | p value | |
|---|---|---|---|
| SGA | 8 (5.19%) | 6 (4.72%) | 0.369 |
| IUFD | 5 (3.24%) | 2 (1.57%) | 0.469 |
| PRETERM | 33 (21.42%) | 17 (13.28%) | 0.001 |
| NICU admissions | 28 (18.18%) | 25 (19.68%) | 0.749 |
Fetal and Maternal Outcomes vs Time of Vaccination
| Criteria | 1st Trimester Vaccination (N=27) | 2nd Trimester Vaccination (N=51) | 3rd Trimester Vaccination (N=49) | Total | p value |
|---|---|---|---|---|---|
| NICU admissions | 2 | 9 | 14 | 25 | 0.07 |
| Preterm birth | 3 | 8 | 6 | 17 | 0.81 |
| Gestational and pregestational diabetes | 0 | 1 | 3 | 4 | 0.56 |
| Hypertension in pregnancy | 2 | 5 | 3 | 10 | 0.78 |
| PPROM | 4 | 3 | 4 | 11 | 0.41 |
| Anemia | 3 | 2 | 1 | 6 | 0.19 |
APGAR Scores
| APGAR Scores | Unvaccinated (Live births=149) | Vaccinated (Live births=125) | p value |
|---|---|---|---|
| 1 min score <7 | 9 (6.04%) | 15 (12%) | 0.66 |
| 5 min score <7 | 2 (1.34%) | 5 (4%) |
Demographic and Obstetric Parameters
| Parameters | Unvaccinated N=154 | Vaccinated N=127 | p value |
|---|---|---|---|
| Age | 28.12 ± 4.6 | 28.24 ± 4.1 | 0.81 |
| Gravidity | |||
| <3 | 121 (78.57) | 107 (84.25) | |
| ≥3 | 33 (21.43) | 20 (15.75) | 0.29 |
| Parity | |||
| 0 | 108 (70.12) | 89 (70.07) | |
| 1 | 40 (25.97) | 34 (26.77) | |
| 2 | 5 (3.24) | 4 (3.14) | |
| 3 | 1 (0.64) | 0 (0) | 0.839 |
| Abortion | |||
| ≤1 | 142 (92.20) | 117 (92.12) | |
| >2 | 12 (7.80) | 10 (7.88) | 0.561 |
| Gestational age at delivery | 37.6 ± 2.4 | 37.1 ± 2.1 | 0.033 |
| Multifetal gestation | 3 (1.94) | 6 (4.72) | 0.704 |
| Previous LSCS | 17 (11.03) | 15 (11.81) | 0.839 |
Adverse Reactions Associated with COVID-19 Vaccines
| Symptoms | Covaxin | Covishield |
|---|---|---|
| Fever | 3 | 5 |
| Headache | 9 | 2 |
| Injection site pain | 1 | 0 |
| Myalgia | 6 | 5 |
| Vomiting | 2 | 1 |
| TOTAL | 21 (30%) | 13 (22.8%) |