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Is immunization with palivizumab really effective in high-risk children? Cover

Is immunization with palivizumab really effective in high-risk children?

Open Access
|Feb 2023

Figures & Tables

Figure 1

The distribution of the total number of immunized children during the period of study 2008–2022 in Clinic of Child Disease UHC Mostar.
The distribution of the total number of immunized children during the period of study 2008–2022 in Clinic of Child Disease UHC Mostar.

Figure 2

The number of immunized children readmitted for infections of the lower respiratory system during the study period 2008–2022 in Clinic of Child Disease UHC Mostar.
The number of immunized children readmitted for infections of the lower respiratory system during the study period 2008–2022 in Clinic of Child Disease UHC Mostar.

National guidance based on earlier research and recommendations by the AAP:

Primary recommendations for immunizationScore*Individual risk factorsScore
Preterm infants with a gestational age (GA) < 29 weeks in the RSV season4Neurological disorders1
Infants with bronchopulmonary dysplasia (BPD) < 2 years of age if they were undergoing therapy for BPD in the RSV season4Birth weight less than 1500 g1
Infants with a congenital heart defect (HS-CHD) < 2 years of age in the RSV season4Mechanical ventilation for a period of 48 hours prior to the commencement of the RSV season;1
Preterm infants with a GA >29<32 weeks (< 6 months of the RSV season with *individual risk factors2Discharged in the period from November 1 to March 311
Immunodeficiency4Low social status0.5
Visits to kindergarten0.5
Twins0.5
Exposure to smoke0.5

Demographic characteristics of children who received passive immunization during the study period 2008–2022 in Clinic of Child Disease UHC Mostar_

Children with CHD n=69Preterm infants n=124Children with other diagnosis n=29Total n=222
Male3956.5%6955.6%2069.0%12857.7%
Female3043.5%5544.4%931.0%9442.3%
Gestational age (weeks+days)
< 29 +6d00.0%4737.9%13.4%4821.6%
30-32 +6d22.9%6451.6%26.9%6830.6%
33-37 +6d913.0%1310.5%1241.4%3415.3%
38-41 +6d5884.1%00.0%1448.3%7232.4%
Birthweight (g)
<100000.0%2116.9%00.0%219.5%
1001-150011.4%6552.4%00.0%6629.7%
1501-25001115.9%3729.8%1034.5%5826.1%
>25005782.6%10.8%1965.5%7734.7%
Mechanicalventilation
Yes2637.7%9778.2%2275.9%14565.3%
No4362.3%2721.8%724.1%7734.7%
Parityofmother
Primiparous3144.9%7560.5%1448.3%12054.1%
Multiparous3855.1%4939.5%1551.7%10245.9%
Pregnancy 0.0%
Singletones6594.2%8165.3%2689.7%17277.5%
Multiplepregnancy45.8%4334.7%310.3%5022.5%
DOI: https://doi.org/10.34763/jmotherandchild.20222601.d-22-00049 | Journal eISSN: 2719-535X | Journal ISSN: 2719-6488
Language: English
Page range: 87 - 92
Submitted on: Oct 9, 2022
Accepted on: Jan 12, 2022
Published on: Feb 22, 2023
Published by: Institute of Mother and Child
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2023 Marjana Jerković Raguž, Tomica Božić, Tamara Nikše, published by Institute of Mother and Child
This work is licensed under the Creative Commons Attribution 4.0 License.