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Is immunization with palivizumab really effective in high-risk children? Cover

Is immunization with palivizumab really effective in high-risk children?

Open Access
|Feb 2023

Figures & Tables

Table 1

National guidance based on earlier research and recommendations by the AAP:

Primary recommendations for immunizationScore*Individual risk factorsScore
Preterm infants with a gestational age (GA) < 29 weeks in the RSV season4Neurological disorders1
Infants with bronchopulmonary dysplasia (BPD) < 2 years of age if they were undergoing therapy for BPD in the RSV season4Birth weight less than 1500 g1
Infants with a congenital heart defect (HS-CHD) < 2 years of age in the RSV season4Mechanical ventilation for a period of 48 hours prior to the commencement of the RSV season;1
Preterm infants with a GA >29<32 weeks (< 6 months of the RSV season with *individual risk factors2Discharged in the period from November 1 to March 311
Immunodeficiency4Low social status0.5
Visits to kindergarten0.5
Twins0.5
Exposure to smoke0.5
Table 2

Demographic characteristics of children who received passive immunization during the study period 2008–2022 in Clinic of Child Disease UHC Mostar.

Children with CHD n=69Preterm infants n=124Children with other diagnosis n=29Total n=222
Male3956.5%6955.6%2069.0%12857.7%
Female3043.5%5544.4%931.0%9442.3%
Gestational age (weeks+days)
< 29 +6d00.0%4737.9%13.4%4821.6%
30-32 +6d22.9%6451.6%26.9%6830.6%
33-37 +6d913.0%1310.5%1241.4%3415.3%
38-41 +6d5884.1%00.0%1448.3%7232.4%
Birthweight (g)
<100000.0%2116.9%00.0%219.5%
1001-150011.4%6552.4%00.0%6629.7%
1501-25001115.9%3729.8%1034.5%5826.1%
>25005782.6%10.8%1965.5%7734.7%
Mechanicalventilation
Yes2637.7%9778.2%2275.9%14565.3%
No4362.3%2721.8%724.1%7734.7%
Parityofmother
Primiparous3144.9%7560.5%1448.3%12054.1%
Multiparous3855.1%4939.5%1551.7%10245.9%
Pregnancy0.0%
Singletones6594.2%8165.3%2689.7%17277.5%
Multiplepregnancy45.8%4334.7%310.3%5022.5%
Figure 1

The distribution of the total number of immunized children during the period of study 2008–2022 in Clinic of Child Disease UHC Mostar.

Figure 2

The number of immunized children readmitted for infections of the lower respiratory system during the study period 2008–2022 in Clinic of Child Disease UHC Mostar.

DOI: https://doi.org/10.34763/jmotherandchild.20222601.d-22-00049 | Journal eISSN: 2719-535X | Journal ISSN: 2719-6488
Language: English
Page range: 87 - 92
Submitted on: Oct 9, 2022
Accepted on: Jan 12, 2022
Published on: Feb 22, 2023
Published by: Institute of Mother and Child
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2023 Marjana Jerković Raguž, Tomica Božić, Tamara Nikše, published by Institute of Mother and Child
This work is licensed under the Creative Commons Attribution 4.0 License.