Fig. 1
Additional anomalies detected in the assessed group of patients_Tabela II_ Dodatkowe anomalie stwierdzone u pacjentów w badanej grupie_
| With heart defect | Without heart defect | |
|---|---|---|
| Gastrointestinal system anomalies | ||
| Hirschsprung Choroba Hirschsprungadisease | 4 | 4 |
| Duodenal Atrezja dwunastnicy atresia | 2 | 6 |
| Hirschsprung and Duodenal atresia | 1 | 0 |
| Anal Atrezja atresia | 1 | 0 |
| Total/Ogółem | 8 2.7% | 10 4.8% |
| Urinary system anomalies | ||
| Cryptorchidism | 3 | 2 |
| Megaureter | 0 | 2 |
| Kidney Hipoplazja hypoplasia | 2 | 0 |
| Total/Ogółem | 5 1.7% | 4 1.9% |
| Eye anomalies | ||
| Cataract | 1 | 3 |
| Total/Ogółem | 1 0.3% | 3 1.4% |
| Nervous system anomalies | ||
| Agenesis of vermis cerebellar | 0 | 1 |
| Total/Ogółem | 0 | 1 0.5% |
| Haematological anomalies | ||
| Thrombocytopenia | 6 | 9 |
| Transient myeloproliferative disorderPrzejściowy zespół mieloproliferacyjny | 2 | 3 |
| ALL | 2 | 3 |
| AML | 3 | 0 |
| Total/Ogółem | 13 4.5% | 15 7.1% |
Specific heart defects in the studied group of patients and in the historical cohort described by Malec et al_Tabela I_ Specyfika wad serca w badanej grupie pacjentów i w grupie opisanej przez Malec i wsp_
| This study (500 patients) Badana grupa (500 pacjentów) | Study by Malec et al. (100 patients) Grupa opisana przez Malec i wsp. (100 pacjentów) | Statistical significance of differences between cohorts (Fisher’s exact test) | |
|---|---|---|---|
| Congenital heart defects usually requiring early surgical treatment Wrodzone wady serca wymagające zazwyczaj wczesnej interwencji kardiochirugicznej | 215 (74.6%) | 89 (89%) | |
| Common atrioventricular canal (CAVC) | 101 (35.1%) | 54 (60.6%) | p=0.032 |
| Ventricular septal defect (VSD) | 78 (27.1%) | 24 (26.9%) | ns |
| Tetralogy of Fallot (ToF) | 13 (4.9%) | 8 (8.08%) | ns |
| Patent ductus arteriosus (PDA) | 19 (6.6%) | 3 (3.3%) | ns |
| Transposition of great arteries (TGA), isolated abnormalities of pulmonary arteries | 4 (1.4%) | 0 (0) | ns |
| Other defects (surgical treatment usually in older children or not required) Inne defekty (wymagające zazwyczaj zabiegów kardiochirurgicznych w późniejszym wieku lub niewymagające zabiegu) | 73 (25.3%) | 11 (11%) | |
| Atrial septal defect ostium primum (ASD I) | 10 (13.6%) | 8 (8.08%) | Not assessed |
| Atrial septal defectostium secundum (ASD II ) | 63 (86.2%) | 3 (3.3%) | Not assessed |
| No congenital heart defect Bez wrodzonych wad serca | 212 (42.4%) | No data |