Have a personal or library account? Click to login
Classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency – The next disease included in the neonatal screening program in poland Cover

Classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency – The next disease included in the neonatal screening program in poland

Journal of Mother and Child
Volume 22 (2018): Issue 2 (June 2018)
By: Maria Ginalska-Malinowska  
Open Access
|Jun 2018

Figures & Tables

Fig. 1

Schematic diagram of adrenal steroidogenesis Steroidogenic enzymes (in frames): StAR - steroidogenic acute regulatory protein 17-OH - 17α-hydroxylase/17,20-lyase 3β-HSD - 3β-hydroxysteroid dehydrogenase 21-OH - 21-hydroxylase 11-OH - 11β-hydroxylase AS - aldosterone synthase 17β-HSD - 17β-hydroxysteroid dehydrogenase Hormones: DOC - 11-deoxyorticosterone; DHEA – dehydroepiandrosterone; Ryc. 1. Schemat steroidogenezy nadnerczowej Enzymy steroidogenezy (w ramkach): StAR - steroidowe ostre białko regulatorowe 17-OH - 17α-hydroksylaza/17,20-liaza 3β-HSD - dehydrogenaza 3β-hydroksysteroidowa 21-OH - 21-hydroksylaza 11-OH - 11β-hydroksylaza AS - syntaza aldosteronowa 17β-HSD - dehydrogenaza 17β-hydroksysteroidowa Hormony: DOC - 11-deoksykortykosteron; DHEA – dehydroepiandrosteron;
Schematic diagram of adrenal steroidogenesis Steroidogenic enzymes (in frames): StAR - steroidogenic acute regulatory protein 17-OH - 17α-hydroxylase/17,20-lyase 3β-HSD - 3β-hydroxysteroid dehydrogenase 21-OH - 21-hydroxylase 11-OH - 11β-hydroxylase AS - aldosterone synthase 17β-HSD - 17β-hydroxysteroid dehydrogenase Hormones: DOC - 11-deoxyorticosterone; DHEA – dehydroepiandrosterone; Ryc. 1. Schemat steroidogenezy nadnerczowej Enzymy steroidogenezy (w ramkach): StAR - steroidowe ostre białko regulatorowe 17-OH - 17α-hydroksylaza/17,20-liaza 3β-HSD - dehydrogenaza 3β-hydroksysteroidowa 21-OH - 21-hydroksylaza 11-OH - 11β-hydroksylaza AS - syntaza aldosteronowa 17β-HSD - dehydrogenaza 17β-hydroksysteroidowa Hormony: DOC - 11-deoksykortykosteron; DHEA – dehydroepiandrosteron;

Fig. 2

Schematic diagram of adrenal steroidogenesis in 21-hydroxylase deficiency Steroidogenic enzymes (in frames): StAR - steroidogenic acute regulatory protein 17-OH - 17α-hydroxylase/17,20-lyase 3β-HSD - 3β-hydroxysteroid dehydrogenase 21-OH - 21-hydroxylase 11-OH - 11β-hydroxylase AS - aldosterone synthase 17β-HSD - 17β-hydroxysteroid dehydrogenase Hormones: DOC - 11-deoxyorticosterone; DHEA – dehydroepiandrosterone Ryc. 2. Schemat steroidogenezy nadnerczowej przy niedoborze 21-hydroksylazy Enzymy steroidogenezy (w ramkach): StAR - steroidowe ostre białko regulatorowe 17-OH - 17α-hydroksylaza/17,20-liaza 3β-HSD - dehydrogenaza 3β-hydroksysteroidowa 21-OH - 21-hydroksylaza 11-OH - 11β-hydroksylaza AS - syntaza aldosteronowa 17β-HSD - dehydrogenaza 17β-hydroksysteroidowa Hormony: DOC - 11-deoksykortykosteron; DHEA – dehydroepiandrosteron
Schematic diagram of adrenal steroidogenesis in 21-hydroxylase deficiency Steroidogenic enzymes (in frames): StAR - steroidogenic acute regulatory protein 17-OH - 17α-hydroxylase/17,20-lyase 3β-HSD - 3β-hydroxysteroid dehydrogenase 21-OH - 21-hydroxylase 11-OH - 11β-hydroxylase AS - aldosterone synthase 17β-HSD - 17β-hydroxysteroid dehydrogenase Hormones: DOC - 11-deoxyorticosterone; DHEA – dehydroepiandrosterone Ryc. 2. Schemat steroidogenezy nadnerczowej przy niedoborze 21-hydroksylazy Enzymy steroidogenezy (w ramkach): StAR - steroidowe ostre białko regulatorowe 17-OH - 17α-hydroksylaza/17,20-liaza 3β-HSD - dehydrogenaza 3β-hydroksysteroidowa 21-OH - 21-hydroksylaza 11-OH - 11β-hydroksylaza AS - syntaza aldosteronowa 17β-HSD - dehydrogenaza 17β-hydroksysteroidowa Hormony: DOC - 11-deoksykortykosteron; DHEA – dehydroepiandrosteron
DOI: https://doi.org/10.34763/devperiodmed.20182202.197200 | Journal eISSN: 2719-535X | Journal ISSN: 2719-6488
Journal RSS Feed
Language: English
Page range: 197 - 200
Submitted on: Mar 20, 2018
Accepted on: May 7, 2018
Published on: Jun 30, 2018
Published by: Institute of Mother and Child
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year
Keywords:
congenital adrenal hyperplasia,
CAH,
21-hydroxylase deficiency,
neonatal screening
Related subjects:
Medicine,
Clinical medicine,
Pediatrics and juvenile medicine,
Paediatric haematology and oncology,
Public health

© 2018 Maria Ginalska-Malinowska, published by Institute of Mother and Child
This work is licensed under the Creative Commons Attribution 4.0 License.

Previous articleVolume 22 (2018): Issue 2 (June 2018)Next article