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Changes in the Protein Profile in Staphylococcal Strains from Patients Infected with the SARS-CoV-2 Virus Cover

Changes in the Protein Profile in Staphylococcal Strains from Patients Infected with the SARS-CoV-2 Virus

Open Access
|Feb 2023

Figures & Tables

graphic/j_pjm-2023-001_ufig_001.jpg
Table I

Clinical characteristics of patients.

Age
(median)
Oxygen
saturation
(median)
CRP
(median)
Diabetes
(n of patients)
Hypertension
(n of patients)
n
Patients hospitalized due to SARS-CoV-2 infection719061,46812
Patients with wound infection (diabetes, SARS-CoV-2 negative)64N/AN/A17N/A17
S. aureus carriers (diabetes)58N/AN/A11N/A11
Table II

Characteristics of the protein peaks identified in the study. The m/z value refers to the mass/charge ratio.

m/zLiteratureRelative peak intensity
2,151This studyN = 7
Med 14
2,430This studyN = 6
Med 11.5
2,515This studyN = 14
Med 11.5
2,652This studyN = 23
Med 14
2,750This studyN = 8
Med 15.5
2,770Sauget et al. 2017N = 24
Med 15
2,869This studyN = 23
Med 13
2,895This studyN = 2
Med 15
3,005Jackson et al. 2005;
Østergaard et al. 2010;
Böhme et al. 2012;
Josten et al. 2013
N = 15
Med 26
3,177This studyN = 12
Med 13,5
3,212This studyN = 17
Med 16
3,410This studyN = 30
Med 25
3,445Bernardo et al. 2002;
Østergaard et al. 2010;
Böhme et al. 2012;
Josten et al. 2013
N = 40
Med 49
3,785This studyN = 9
Med 11
4,307This studyN = 40
Med 28
4,458Østergaard et al. 2010;N = 6
Med 13
4,594Østergaard et al. 2010;N = 3
Med 11
4,819Østergaard et al. 2010;
Sauget et al. 2017
Med 30.5
N = 28
5,035Bernardo et al. 2002;
Jackson et al. 2005;
Østergaard et al. 2010;
Böhme et al. 2012;
Josten et al. 2013
N = 36
Med 36.6
5,306Sauget et al. 2017N = 19
Med 17
5,528Bernardo et al. 2002;
Østergaard et al. 2010;
Böhme et al. 2012;
Josten et al. 2013;
Jackson et al. 2020
N = 30
Med 43.5
5,554Sauget et al. 2017N = 6
Med 23
6,032Østergaard et al. 2010N = 3
Med 23
6,357This studyN = 29
Med 13
6,426Østergaard et al. 2010N = 10
Med 11
6,575Jackson et al. 2005;
Østergaard et al. 2010;
Böhme et al. 2012;
Josten et al. 2013
N = 17
Med 12
6,820Sauget et al. 2017N = 38
Med 54
6,892Østergaard et al. 2010;
Böhme et al. 2012
Med 100
N = 40
9,632Østergaard et al. 2010;
Sauget et al. 2017
N = 26
Med 28
Fig. 1.

Classification and Regression Trees of the strains studied by the protein presence and relative amount of particular protein. Red boxes represent the identified categories, while vertical bars are the source of strains.

Fig. 2.

ANOVA comparison of relative protein peak intensity in isolates from different groups of patients.

DOI: https://doi.org/10.33073/pjm-2023-001 | Journal eISSN: 2544-4646 | Journal ISSN: 1733-1331
Language: English
Page range: 93 - 99
Submitted on: Sep 23, 2022
Accepted on: Dec 3, 2022
Published on: Feb 21, 2023
Published by: Polish Society of Microbiologists
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2023 TOMASZ JARZEMBOWSKI, LIDIA PIECHOWICZ, MAREK BRONK, ANNA PAŁUBICKA, ŁUKASZ NAUMIUK, published by Polish Society of Microbiologists
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.