Fig. 1
Baseline characteristics of the study population_
| Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | |
|---|---|---|---|---|---|
| Age (y) | 84 | 46 | 62 | 65 | 57 |
| Gender | male | male | male | female | male |
| Bed code | J01 | 23 | 18 | 22 | J07 |
| Diagnosis | traumatic brain injury | spontaneous intracerebral hemorrhage | spontaneous intracerebral hemorrhage | traumatic brain injury | thalamic hemorrhage |
| Date of ICU admission | 9 June | 3 June | 1 June | 31 May | 14 May |
| Analyzed sample | sputum | sputum | sputum | sputum | sputum |
| Date of sample analysis | June 13 | June 17 | June 13 | June 11 | June 17 |
| Pathogen | AB (+++) | AB (+++) | AB (+++) | AB (++) | AB (++) KP (+++) |
| Date of tracheostomy | June 18 | June 6 | no | May 31 | May 17 |
| Duration of invasive mechanical ventilation | 3 | 30 | N/A | 8 | 23 |
| Antibiotic combination therapy | yes | yes | yes | yes | yes |
| NI or colonization | NI | colonization | colonization | NI | colonization |
Suspected alert rates for infections or outbreaks in different periods_
| Periods | Number of suspected infections | Number of ICU patients | Rate of suspected infections | χ2 | p-value |
|---|---|---|---|---|---|
| 11–17 June 2019 | 5 | 42 | 11.9% | 0.267 | 0.875 |
| 20 May – 20 June 2018 | 6 | 38 | 15.8% | ||
| 20 April – 20 May 2019 | 6 | 41 | 14.6% |
Drug susceptibility of multidrug-resistant bacteria isolated from the patients_
| Antibiotics | Case 1 | Case 2 | Case 3 | Case 4 | Case 5 |
|---|---|---|---|---|---|
| Ampicillin/sulbactam | R | R | R | R | R |
| Ceftazidime | R | R | R | R | R |
| Ceftriaxone | R | R | R | R | R |
| Cefepime | R | R | R | R | R |
| Imipenem | R | R | R | R | R |
| Gentamicin | R | R | R | R | R |
| Tobramycin | S | R | R | S | S |
| Ciprofloxacin | R | R | R | R | R |
| Levofloxacin | R | R | R | R | R |
| Sulfamethoxazole | S | R | R | S | R |