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Fungal Infections in COVID-19 Intensive Care Patients Cover

Fungal Infections in COVID-19 Intensive Care Patients

Open Access
|Sep 2021

Figures & Tables

Table I

Descriptive variables related to patients.

Demographic variablesN or X
(Mean, min-max)
%
or Mean ± SD
Gender
    Female825.0
    Male2475.0
Age (year)73.50 (52-94)73.43 ± 10.14
    50-59412.5
    60-791650.0
    ≥ 801237.5
BMI* (kg/m2)
    Female28.89 (20.41-44.44)
    Male27.68 (20.76-44.98)
Smoking status
    Female225.0
    Male1458.33

1 *BMI – Body Mass Index

Table II

Isolation of fungi from the clinical specimens.

Specimen*
(n = 57)
Fungal isolate
(n)
%
Blood1623.2
Aspirate1217.4
Urine2942.1
Urine + blood  811.6
Aspirate + blood  3  4.4
Aspirate + urine  1  1.3

2 * – Since the categories were multiple-response,

3     N exceeded the sample size.

Table III

Distribution of candidemia cases by hospitalization days.

Mean ± SD
7.56 ± 25.62
(min-max: 1-136)
NN (%)
1-30days  425
> 30 days1275
Table IV

Distribution of fungal infection cases based on accompanying diseases.

Accompanying disease
(n = 52)
Number of patients
N (%)
Diabetes mellitus11 (34.4)
Cardiovascular disease*22 (68.8)
Respiratory disease6 (18.8)
Neurological disease11 (34.4)
Renal disease1 (3.1)

4 * – Cardiovascular disease: coronary artery disease, hypertension, heart failure

Table V

Distribution of fungal infection cases by risk factors.

Number of Patients
N (%)
Fungal Isolate
N (%)
Parenteral nutrition
No25 (78.1)45 (78.95)
Yes  7 (21.9)12 (21.05)
Steroid use
No20 (62.5)44 (77.19)
Yes12 (37.5)13 (22.81)
ICU insulin use
No12 (37.5)24 (42.11)
Yes20 (62.5)33 (57.89)
Central venous catheter
No14 (43.75)45 (78.95)
Yes18 (56.25)12 (21.05)
Table VI

Distribution of fungal species in blood, tracheal aspirate, and urine cultures.

Fungus typesFungal isolate
N (%)
Blood
N (%)
Tracheal aspirate
N (%)
Urine
N (%)
Total: 16Total: 12Total: 29
Candida tropicalis20 (35.08)5 (31.25)4 (33.33)11 (37.93)
Candida albicans18 (31.58)4 (25.00)0 (0.00)14 (48.27)
Candida parapsilosis14 (24.56)7(43.75)3 (25)  4 (13.79)
Aspergillus spp.3 (5.28)0 (0.00)3 (25)0 (0.00)
Candida lusitaniae1 (1.75)0 (0.00)  1 (8.34)0 (0.00)
Trichosporon mucoides1 (1.75)0 (0.00)  1 (8.34)0 (0.00)
Table VII

Antibiotics used by patients with fungal infection and days.

Used antibiotics groupsNumber of patients
N (%)
Days of using antibiotic before fungal infection
Carbapenem32 (100%)      17 ± 12.52
Glycopeptide32 (100%)      13 ± 7.4
Linezolid  23 (71.87%)      10 ± 7.30
Quinolone11 (33.3%)      14 ± 7.20
Tigecycline    8 (24.24%)      12 ± 5
Aminoglycoside  2 (6.06%)      10 ± 2.3
DOI: https://doi.org/10.33073/pjm-2021-039 | Journal eISSN: 2544-4646 | Journal ISSN: 1733-1331
Language: English
Page range: 395 - 400
Submitted on: Jun 24, 2021
Accepted on: Aug 9, 2021
Published on: Sep 17, 2021
Published by: Polish Society of Microbiologists
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2021 AYŞENUR SÜMER COŞKUN, ŞENAY ÖZTÜRK DURMAZ, published by Polish Society of Microbiologists
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.