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Prevalence of Multi-Drug Resistant Mycobacterium Tuberculosis in Khyber Pakhtunkhwa – A High Tuberculosis Endemic Area of Pakistan Cover

Prevalence of Multi-Drug Resistant Mycobacterium Tuberculosis in Khyber Pakhtunkhwa – A High Tuberculosis Endemic Area of Pakistan

Open Access
|Apr 2020

Figures & Tables

Table I

Association of TB with gender, different age groups and treatment history, p-value of < 0.05 shows a statistical significance.

CharacterTB SuspectsPositive cases p-value
Gender
Male3189947 (29%)χ (3) = 68.2, p = 0.005
Female25701022 (39%)
Age group
01–1443796 (22%)
15–241137396 (34%)
25–341180473 (40%)
35–44827298 (26%)
45–54732227 (31%)
55–64819282 (34.4%)
65–100627197 (31.4%)
Treatment history
Previously Treated1024461 (45%)χ (3) = 68, p-value = 0.05
Never Treated39221508 (38%)
Disease type
Pulmonary52901864 (35%)χ (3) = 68, p-value < 0.05
Extra Pulmonary469105 (22%)
Sample type
Ascetic Fluid9110 (11%)χ (36) = 259.6, p-value ≤ 0.05
BAL* 17245 (26%)
Bone202 (10%)
CSF ** 442 (5%)
Gastric Lavage685 (7%)
Lymph Node103 (30%)
Pericardial fluid263 (12%)
Pleural Fluid17226 (15%)
Pus549 (17%)
Sputum50331858 (37%)
Synovial Fluid30 (0%)
Tissue205 (25%)
Urine461 (2%)

1* Bronchoscopy alveolar lavages,

2** Cerebrospinal fluid

Table II

Correlation of the MDR-TB prevalence with patient’s age, gender, and previous treatment history.

CharacterTotal DSTDiagnosed with DR-TB p-value
Gender
Male116761 (5.2%)χ (1) = 1, p = 0.26
Female80036 (4.5%)
Age group
01–141865 (2.6%)χ (5.8) = 6, p = 0.445
15–2433320 (6%)
25–3437218 (4.8%)
35–4427911 (4%)
45–5425810 (3.8%)
55–6429419 (6.4%)
65–10024514 (5.7%)
Treatment history
NT* 150849 (3.2%)χ (16) = 2, p-value = 0.001
PT ** 46148 (10.4%)
Disease type
Pulmonary177194 (5.3%)χ (5.3) = 1, p-value = 0.009
Extra Pulmonary1963 (1.5%)

3* NT = Never treated;

4** PT = previously treated;

5 DST = drug susceptibility testing; DR-TB = drug resistant tuberculosis

DOI: https://doi.org/10.33073/pjm-2020-005 | Journal eISSN: 2544-4646 | Journal ISSN: 1733-1331
Language: English
Page range: 133 - 137
Submitted on: Oct 24, 2019
Accepted on: Jan 8, 2020
Published on: Apr 6, 2020
Published by: Polish Society of Microbiologists
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2020 SAJID ALI, MUHAMMAD TAHIR KHAN, ANWAR SHEED KHAN, NOOR MOHAMMAD, MUHAMMAD MUMTAZ KHAN, SAJJAD AHMAD, SADIQ NOOR, ABDUL JABBAR, CANTILLON DAIRE, FARIHA HASSAN, published by Polish Society of Microbiologists
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.